宫颈癌可疑复发转移诊断中血清鳞状上皮细胞癌抗原、PET-CT单用或联用价值分析  

Value of serum squamous cell carcinoma antigen, PET-CT alone or in combination in diagnosis of suspicious recurrence and metastasis of cervical cancer

作　　者：甘西伦[1] 杨建波[1] 谭蓓蓓[1] 王明霜 

机构地区：[1]四川泸州医学院附属医院核医学科,四川泸州646000

出　　处：《中国现代医学杂志》2015年第6期52-55,共4页China Journal of Modern Medicine

摘　　要：目的探讨宫颈癌可疑复发转移诊断中血清鳞状上皮细胞癌抗原、PET-CT单用或联用价值差异。方法选取宫颈癌术后可疑复发患者90例,依次行PET-CT、血清鳞状上皮细胞癌抗原检查;比较两种检查方式诊断宫颈癌复发或转移灶与病理结果符合情况。结果有淋巴结转移的宫颈癌患者术后复发转移风险明显高于术前无淋巴结转移宫颈癌患者,差异有统计学意义(P<0.05);血清鳞状上皮细胞癌抗原升高宫颈癌患者术后复发转移风险明显高于血清鳞状上皮细胞癌抗原正常宫颈癌患者,差异有统计学意义(P<0.05);PET-CT诊断宫颈癌术后复发转移风险特异度显著高于血清鳞状上皮细胞癌抗原检测,差异有统计学意义(P<0.05)。结论对于术前淋巴结转移和血清鳞状上皮细胞癌抗原升高宫颈鳞癌患者术后应行PET-CT检查,以提高可疑复发转移检出准确度。【Objective】To investigate the differences in the value of serum squamous cell carcinoma antigen,PET-CT alone or in combination in the diagnosis of suspicious recurrence and metastasis of cervical cancer.【Methods】A total of 90 patients with suspicious recurrence and metastasis of cervical cancer were chosen for the test of serum squamous cell carcinoma antigen, PET-CT. And the coincidence degree of diagnosis of cervical cancer recurrence and metastasis by the two testing methods with pathological results was compared.【Results】The recurrence and metastasis risk of the patients with cervical carcinoma and lymph node metastasis was significantly higher than that of the patients with cervical carcinoma and no lymph node metastasis（P〈0.05）. The recurrence and metastasis risk of the patients with cervical carcinoma and increased serum squamous cell carcinoma antigen level was significantly higher than that of the patients with cervical carcinoma and normal serum squamous cell carcinoma antigen level（P〈0.05）. The specificity of PET-CT alone or in combination for the diagnosis of cervical cancer suspicious recurrence and metastasis was significantly higher than that of serum squamous cell carcinoma antigen detection（P〈0.05）.【Conclusions】Cervical cancer patients with lymph node metastasis and increased serum squamous cell carcinoma antigen level before operation need PET-CT examination in order to improve the detection accuracy of suspicious recurrence and metastasis.

关 键 词：宫颈癌 复发转移 血清鳞状上皮细胞癌抗原 PET-CT 

分 类 号：R737.33[医药卫生—肿瘤]