79例成人连续部分性癫痫患者临床分析  

Clinical analysis of 79 adult patients with epilepsia partialis continua

作　　者：陈东平[1] 侯淑红[1] 陈衍贵[1] 陈明生[1] 

机构地区：[1]福建医科大学附属龙岩第一医院,龙岩364000

出　　处：《中国实用神经疾病杂志》2015年第3期7-9,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨成人连续部分性癫痫（EPC）的临床特征。方法回顾性分析79例成人EPC患者的临床特征,评价治疗结果。结果所有患者均表现为不伴意识障碍的运动性部分性癫痫持续状态。EPC平均持续时间6.3d（1-28d）,最常累及部位为面臂部（33例,41.8%）。最常见病因为高血糖（35例,44.3%）。预后良好54例（68.4%）,预后不良25例（31.6%）。所有病因为高血糖的患者预后良好,无需长期抗癫痫治疗。预后良好的相关因素为代谢性疾病或高血糖导致的EPC、单药治疗和EPC持续时间。结论 EPC最常见病因为高血糖,预后依赖于病因、使用的抗癫痫药物种类和EPC持续时间。Objective To explore the clinical features of epilepsia partialis continua（EPC）in adult patients.MethodsThe clinical features of 79 adult patients with EPC were analyzed retrospectively and the therapeutic outcomes were evaluated.Results All patients manifested as motor partial status epilepticus without impairment of consciousness.The mean duration of EPC was 6.3days,ranging from 1to 28 days.The most frequent distribution of EPC involved the face and arms（33patients,41.8%）.Hyperglycemia was the most common cause of EPC（35patients,44.3%）.Fifty-four patients（68.4%）had an excellent outcome and 25patients（31.6%）had a non-excellent outcome.All patients with hyperglycemia had an excellent outcome and required no antiepileptics in the long term.Predictors of excellent outcome were metabolic or hyperglycemia-induced EPC,monotherapy and duration of EPC.Conclusion The most common cause of EPC was hyperglycemia and prognostic factors depended on etiology,number of antiepileptic drugs and duration of EPC.

关 键 词：连续部分性癫痫 临床特征 病因 预后 

分 类 号：R742.1[医药卫生—神经病学与精神病学]