缺血性脑卒中发生早期神经功能恶化(END)的相关因素分析  

Analysis of the risk factors related to early neurological deterioration in patients with ischemic stroke

作　　者：周芬芬[1] 

机构地区：[1]广东惠州市中心人民医院神经内科,惠州516000

出　　处：《中国实用神经疾病杂志》2015年第3期20-22,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨缺血性脑卒中发生早期神经功能恶化(END)的相关因素。方法回顾性分析我院2010-04—2013-01收治的132例缺血性脑卒中患者的临床资料,按是否发生早期神经功能恶化分为早期神经功能恶化组和非早期神经功能恶化组,采用单因素方差分析和多因素Logistic回归分析2组患者一般资料和各项指标,总结发生早期神经功能恶化的相关因素。结果 132例缺血性脑卒中患者发生早期神经功能恶化35例(26.5%)。经多因素Logistic回归分析发现,NIHSS评分高、糖尿病、颈动脉狭窄≥50%、心房颤动以及高血压是影响缺血性脑卒中发生早期神经功能恶化的重要危险因素(P<0.05)。结论 NIHSS评分高、糖尿病、颈动脉狭窄≥50%、心房颤动以及高血压都是影响缺血性脑卒中发生早期神经功能恶化的重要危险因素,对合并以上因素的患者应加强干预治疗,积极改善患者预后。Objective To analyze the risk factors related to early neurological deterioration in patients with ischemic stroke.Methods A retrospective analysis was made on the patients with ischemic stroke in our hospital from 2010 April to2013 January,and the patients were divided into END group and non-END group.Single factor analysis and multiple-factor Logistic regression analysis were employed to analyze the general information and clinical indicators,and then the risk factors related to END were summarized.Results 35 cases of early neural function deterioration occurred in this study of 132 cases of patients with ischemic stroke,the incidence rate was 26.5%.Multiple-factor Logistic regression analysis indicated that the incidence of END could be affected by atrial fibrillation,hypertension,carotid artery stenosis≥50%,diabetes and NIHSS scores.Conclusion Atrial fibrillation,hypertension,carotid artery stenosis≥50%,diabetes and high NIHSS scores are the risk factors that cause early neurological deterioration in patients with ischemic stroke,intervention treatment should be enhanced to improve the prognosis.

关 键 词：缺血性脑卒中 早期神经功能恶化 影响因素 

分 类 号：R743.33[医药卫生—神经病学与精神病学]