血清低密度脂蛋白与急性出血性卒中患者病情的相关性分析  

Analysis of relation between serum low density lipoprotein cholesterol and the pathogenetic condition of patients with acute hemorrhagic stroke

作　　者：邬莹 

机构地区：[1]内蒙古自治区人民医院干部保健所,呼和浩特010020

出　　处：《中国实用神经疾病杂志》2015年第3期31-33,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨血清低密度脂蛋白(LDL-C)和急性出血性卒中患者病情的关系。方法 100例急性出血性卒中患者按照入院时LDL-C水平分成LDL-C<2.49mmol/L组43例与LDL-C≥2.49mmol/L组57例,分析急性出血性卒中患者病情程度与LDL-C水平的相关性。结果 2组患者在凝血酶原时间、收缩压、舒张压、血肿大小、纤维蛋白原、部分活化凝血酶时间、血小板数量以及血糖等生化指标水平比较差异无统计学意义(P>0.05);LDL-C<2.49mmol/L组血肿扩大发生率显著上升,与LDL-C≥2.49mmol/L组相比,差异有统计学意义(P<0.05),且血肿扩大患者的LDL-C水平显著低于无血肿扩大患者,差异有统计学意义(P<0.05)。结论急性出血性卒中患者病情与血清LDL-C水平有关,LDL-C<2.49mmol/L患者容易出现血肿扩大症状,重视入院时血清LDL-C水平的检测有利于预测患者的病情。Objective To investigate the relation between serum low density lipoprotein cholesterol（LDL-C）and the pathogenetic condition of patients with acute hemorrhagic stroke.Methods The clinical data of 100 cases of patients with acute hemorrhagic stroke in our hospital from January 2010 to January 2013 were analyzed retrospectively.All the patients were divided into 43 cases of LDL-C〈2.49mmol/L group and 57 cases of LDL-C≥2.49mmol/L group according to the different levels of LDL-C on admission,and the relationship between pathogenetic condition of patients and serum LDL-C was analyzed.ResultsThe differences in the levels of prothrombin time,systolic blood pressure,diastolic blood pressure,hematoma volume,fibrinogen,active partial thrombin time,platelet counts and blood glucose of two groups were not statistically significant（P〉0.05）.The incidence of hematoma enlargement of LDL-C〈2.49mmol/L group was significantly increased,compared with LDL-C≥2.49mmol/L group,the difference was statistically significant（P〈0.05）,and the level of LDL-C in patients with hematoma enlargement was significantly lower than that of patients without hematoma enlargement,the difference was statistically significant（P〈0.05）.Conclusion The pathogenetic condition of patients with acute hemorrhagic stroke is related with the serum LDL-C level,patients with LDL-C〈2.49mmol/L are prone to occur hematoma enlargement.It should pay much attention to the detection of serum LDL-C on admission,which is helpful to predict the pathogenetic condition.

关 键 词：血清低密度脂蛋白 急性出血性卒中 血肿扩大 

分 类 号：R743.3[医药卫生—神经病学与精神病学]