纳洛酮对急性脑血管意识障碍患者的临床疗效分析  

Curative effect of naloxone on acute cerebrovascular diseases patients with consciousness disturbance

作　　者：田方起[1] 苏兰[1] 王宏昭[1] 潘瑞洪[1] 

机构地区：[1]天津市海滨人民医院(大港油田总医院)神经内科,天津300280

出　　处：《中国实用神经疾病杂志》2015年第1期50-52,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨纳洛酮对急性脑血管意识障碍患者的疗效。方法 86例急性脑血管疾病意识障碍患者随机分为观察组与对照组,各43例,对照组予以常规治疗,观察组在对照组的基础上予以纳洛酮静滴。结果观察组治疗总有效率为90.7%,显著高于对照组的69.8%(P<0.05);2组治疗后神经功能缺陷评分均显著降低,但观察组显著低于对照组(P<0.05);格拉斯哥评分均显著提高,但观察组显著高于对照组(P<0.05)。结论常规治疗的基础上加用纳洛酮可提高急性脑血管意识障碍患者的治疗效果,改善患者的神经功能障碍及昏迷状态,值得推广应用。Objective To investigate the curative effect of naloxone on acute cerebrovascular diseases patients with consciousness disturbance. Methods Totally 86 acute eerebrovaseular diseases patients with consciousness disturbance were randomly divided into observation group （n=43, treated with convention method plus naloxone） and control group （n=43, treated with convention method）. The curative effect of two groups were compared. Results The total effective rate of observation group （90.7 % ） was higher than that of control group （69.8 %）. Compared with control group, observation group had lower neurological function deficits score and higher GCS score after treatment. Conclusion Convention method plus naloxone can increase the curative effect of acute cerebrovascular diseases patients with consciousness disturbance, and improve neurological disorders and narcosis of patients, which is worthy of application.

关 键 词：意识障碍 急性脑血管疾病 纳洛酮 

分 类 号：R743[医药卫生—神经病学与精神病学]