运用Cox比例风险回归模型分析脑出血预后的影响因素  

The risk factors analysis of prognosis of patients with intracerebral hemorrhage by Cox proportional hazard regression model

作　　者：何建明[1] 肖露明 谭建明 戴朝福[2] 王齐[1] 

机构地区：[1]韶关学院医学院附属医院外科,韶关512026 [2]韶关学院医学院临床医学系 [3]广东韶关市第一人民医院神经外科,韶关512000

出　　处：《中国实用神经疾病杂志》2015年第2期1-3,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨运用Cox比例风险回归模型分析脑出血预后危险因素的作用。方法回顾性分析脑出血患者104例,其中死亡组24例,生存组80例,采用SPSS 18.0统计软件作Cox比例风险回归分析2组患者一般情况、刚入院时各项临床、实验室、影像学指标及并发症与脑出血预后的关系。结果多因素Cox比例风险回归分析显示,心脏病史、意识(GCS)、收缩压、舒张压、平均动脉压、血糖、甘油三酯和脑疝形成因素入选回归方程(P<0.05)。结论心脏病史、意识(GCS)、收缩压、舒张压、平均动脉压、血糖、甘油三酯和脑疝形成是影响脑出血患者生命预后的独立影响因素。Objective To investigate the risk factors of prognosis of patients with intracerebral hemorrhage by Cox proportional hazard regression model. Methods The following indexes of 104 patients with intracerebral hemorrhage （including 24 cases of death and 80 cases of survival） were analyzed by using Cox proportion of regression analysis： the general condition, clinical, laboratory and imaging indexes on admission, and complications and prognosis of patients. Results Multivariant Cox ＇s proportional hazard regression showed that the heart disease history, consciousness, systolic blood pressure, diastolic blood pressure, mean arterial pressure, blood glucose, triglycerides and cerebral hernia formation factors were included in the regression equations. Conclusion The heart disease history, consciousness, systolic blood pressure, diastolic blood pressure, mean arterial pressure, blood glucose, triglyeerides and cerebral hernia formation factors are some independent factors on affecting the prognosis of patients with cerebral hemorrhage.

关 键 词：脑出血 预后 影响因素 Cox比例风险回归 

分 类 号：R743.34[医药卫生—神经病学与精神病学]