桥本脑病临床及实验室分析  

Analysis of the clinical and laboratory of patients with Hashimoto's encephalopathy

作　　者：韩新生 张洪阳 张军鸽 韩苗 徐建可 邱刚 王润润 裘丽红 

机构地区：[1]河南开封市中心医院神经内科,开封475000

出　　处：《中国实用神经疾病杂志》2015年第2期36-37,共2页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨桥本脑病的临床、实验室、影像学特点。方法回顾性分析2例桥本脑病的临床资料和治疗效果,结合相关文献进行分析。结果 2例患者均有以记忆力下降为主的认知障碍,颅内均有多发病灶。1例有幻视、癫痫发作和明确的血管狭窄,1例有反复头晕、肢体力弱,无血管狭窄。2例均存在抗甲状腺抗体阳性和甲状腺功能亢进,且糖皮质激素治疗有效。结论认知障碍合并抗甲状腺抗体的增高是本病的特点之一,可以合并颅内血管狭窄,确诊后可早期糖皮质激素治疗。Objective To investigate the clinical, laboratorial and imageological features of patients with Hashimoto＇s encephathy （HE）. Methods The clinical data and curative effect of 2 patients with HE were retrospectively analyzed. Results 2 cases of patients had cognitive impairment with memory deterioration, intracranial multifocal diseases, anti-thyroid antibody, hyperthyroidism and effective glueocorticoids treatment. One patient had visual hallucination, seizures disorder and clear vascular stenosis, the other patient had repeated dizzy, weak body and no vascular stenosis. Conclusion Cognitive impairment with high anti-thyroid antibodies is one of clinical features of patients with HE, and patients often combine intracranial vascular stenosis. HE patients should be treated with glucocorticoids as early as possible.

关 键 词：桥本脑病 认知障碍 抗甲状腺抗体 文献复习 

分 类 号：R742[医药卫生—神经病学与精神病学]