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机构地区:[1]中山大学孙逸仙纪念医院肿瘤科,广州510120
出 处:《中华临床医师杂志(电子版)》2015年第6期73-78,共6页Chinese Journal of Clinicians(Electronic Edition)
基 金:国家自然科学基金(81372819);教育部博士点基金(20120171110075);广州市科技计划(2014J4100170);中山大学青年教师重点培育项目(13ykzd14)
摘 要:乳腺癌是女性最常见的恶性肿瘤之一,其发病率高居女性肿瘤疾病首位,全世界每年约有50万妇女死于乳腺癌。晚期乳腺癌的治疗目标是控制疾病、缓解症状、延长患者生存时间、提高患者生存质量、减少治疗相关毒性。本文介绍了晚期乳腺癌化疗的相关指征、不同化疗方案的选择、后续的维持治疗方案在转移性乳腺癌患者中的应用情况。Breast cancer is the most common cancer in women, which continues to be a major cause of morbidity and mortality among women throughout the world, an estimated 500 000 women died of this disease per year in worldwide. The therapeutic goal of metastatic breast cancer is to control the disease, relieve symptoms, prolong progression free survival, improve the quality of life of patients and reduce treatment-related toxicity. This article recommend the chemotherapy indication of metastatic breast cancer, the effects of different chemotherapy regimens, and the application for subsequent maintenance chemotherpy scheme in patients with metastatic disease.
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