膀胱尿路上皮癌分子标志物的研究进展  

Research progress of molecular markers in bladder urothelial carcinoma

作　　者：王清海[1] 陈志刚[1] 石冰冰[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院泌尿外科,北京100730

出　　处：《基础医学与临床》2015年第3期425-428,共4页Basic and Clinical Medicine

摘　　要：肿瘤标志物作为非侵入性的检查手段不仅可以用于肿瘤诊断和分型,对监测疾病复发和疗效判断等方面也有重要作用。目前现有的检测方法没有达到理想的敏感性和特异性。随着高通量技术的发展,新发现的许多膀胱癌的分子标志物如DNA/RNA类、蛋白质类和代谢产物类或多种标志物的组合为膀胱癌的检测提供了更准确的方法。Tumor markers as a non-invasive examination method not only play very important role in the diagnosis and classification of cancer,but also has an important role to monitor disease recurrence and determine the efficacy of treatment. The current methods do not achieve the desired detection sensitivity and specificity. With the development of high-throughput technology,many molecular markers for bladder cancer have been discovered,such as DNA / RNA,proteins,and metabolites or the combination of them provide a more accurate methods for bladder cancer detection.

关 键 词：膀胱癌 分子标志物 

分 类 号：R737.14[医药卫生—肿瘤]