银杏达莫注射液治疗急性脑梗死的疗效及其对血液流变学的影响  

Effect of Ginkgo Dipyridamole Injection in treating acute cerebral infarction and its influence on hemorrheology

作　　者：陈文华[1] 饶李亮 尹晟[2] 

机构地区：[1]广东省惠州市中医医院药剂科,516001 [2]广东省惠州市中医医院神经内科,516001

出　　处：《检验医学与临床》2015年第6期788-789,792,共3页Laboratory Medicine and Clinic

摘　　要：目的探讨银杏达莫注射液在治疗急性脑梗死中的临床疗效及其对脑血流的改善情况。方法选取2012年4月至2014年4月在惠州市中医医院住院治疗的139例急性脑梗死患者,将其分为观察组(67例)和对照组(72例)。对照组给予降低颅内压、清除自由基、调节血脂、防止血小板聚集等常规治疗,观察组在此基础上给予银杏达莫注射液,比较两组治疗前后神经功能缺损评分及各项血液流变学指标的变化情况。结果治疗后,两组患者神经功能缺损明显减轻,观察组患者神经功能缺损评分低于对照组,差异均有统计学意义(P<0.05);且观察组各项血液流变学指标明显优于对照组,差异均有统计学意义(P<0.05)。结论银杏达莫注射液可有效改善脑血流量,改善血液高黏状态,保护脑组织和神经功能,是治疗急性脑梗死的有效药物,值得在临床使用。Objective To explore the clinical effect of Ginkgo Dipyridamole Injection in treating acute cerebral infarction and its improvement situation on cerebral blood flow.Methods 139 patients with cerebral infarction in our hospital from April 2012 to April 2014 were selected and randomly divided into the observation group（n=67）and the control group（n=72）.The control group was given the conventional treatment of decreasing intracranial pressure,scavenging free radicals,adjusting blood fat and preventing platelet aggregation,etc.,while on the basis of the control group the observation group received Ginkgo Dipyridamole Injection.The neurological deficits scores and hemorrheological indexes before and after treatment were compared between the two groups.Results The neurological deficits after treatment in the two groups were decreased significantly,but the neurological deficits scores in the observation group were lower than those in the control groups,the difference was statistically significant（P〈0.05）.Moreover the various hemorrheological indexes in the observation group were significantly better than those in the control group after treatment（P〈0.05）.Conclusion Ginkgo Dipyridamole Injection can effective improve the cerebral blood flow,improve the high blood viscosity state,protect the brain tissue and nerve function,which is an effective therapeutic drug for treating acute cerebral infarction and deserves to be used in clinic.

关 键 词：脑梗死 血液流变学 银杏达莫注射液 

分 类 号：R743.33[医药卫生—神经病学与精神病学]