颈部彩色超声在食管上段癌放射治疗中的应用  

Application of carotid ultrasonography in radiotherapy of upper esophageal cancer

作　　者：赵庆书 周晶 刘孟奇 吴阔 李永利 

机构地区：[1]邢台矿业集团总医院放疗科,河北邢台054000

出　　处：《河北医科大学学报》2015年第2期166-169,共4页Journal of Hebei Medical University

摘　　要：目的观察颈部彩色超声在食管上段癌调强放射治疗（intensity-modulated radiation therapy,IMRT）中的应用价值。方法选取食管上段癌患者68例,随机分为2组各34例,A组IMRT前行颈部彩色超声检查,发现有淋巴结转移的作为累及野治疗,B组不行彩色超声检查,均采用5个野IMRT。结果放射治疗结束后2组总有效率比较差异无统计学意义（P〉0.05）。2组1年和2年生存率差异无统计学意义（P〉0.05）。A组3年生存率高于B组,差异有统计学意义（P〈0.05）。放射治疗不良反应主要以1~2级为主,2组不良反应发生率比较差异无统计学意义（P〉0.05）。A组病死率低于B组,差异有统计学意义（P〈0.05）。结论在食管上段癌的IMRT前颈部彩色超声检查作为颈部照射野的依据,可提高患者的3年生存率,且近期疗效好,不良反应可耐受。Objective To investigate the use of carotid ultrasonography in the intensitymodulated radiation therapy（IMRT） of upper esophageal cancer.Methods Sixty-eight patients with upper esophageal cancer were divided into group A（experimental group,34 cases） and group B（control group,34 cases）.In group A,the areas were treated by IMRT on condition that lymph nodes metastasis was found.Both groups were performed by IMRT through a 5 field IMRT plan.Results There were no significant differences between two groups in total effective rate（P〈0.05）.The first and second year s survival rate in group A and group B were no significant differences（P〉0.05）.The 3 years＇ rate in group A was distinctly higher than that in group B（P〈0.05）.The side effects of radiotherapy were mainly classified into grade 1 and 2.In addition.no significant differences were noted between the two groups.The fatality rate in group A was remarkably lower than that in group B（P 0.05）.Conclusion Carotid ultrasonography can be used as a basis of neck irradiation in IMRT of upper esophageal carcinoma,which can improve the3 years survival rates with satisfactory recent curative effect and several tolerable toxic side effects.

关 键 词：食管肿瘤 超声检查 多普勒 彩色 放射疗法 

分 类 号：R735.1[医药卫生—肿瘤]