丝裂霉素C结膜下注射联合针拨治疗功能不良滤过泡  

Mitomycin C subconjuctival injection with needling revision on dysfunctional filtering blebs

作　　者：刘贤升 廖文江[1] 闫亚红[1] 欧阳君[1] 柯美魁 

机构地区：[1]中国江西省九江市第一人民医院眼科,332000

出　　处：《国际眼科杂志》2015年第3期549-551,共3页International Eye Science

摘　　要：目的：探讨丝裂霉素C（mitomycin C,MMC）结膜下注射联合针拨治疗青光眼小梁切除术后功能不良滤过泡的疗效。方法：对36例39眼因青光眼行小梁切除术后2~12wk滤过泡功能不良者进行MMC 0.1mL（0.2mg/mL）结膜下注射联合针拨治疗,平均治疗1.31±0.58次,观察眼压、滤过泡和并发症.并随访3mo。结果：治疗后3mo时平均眼压为15.8±6.6mmHg,显著低于治疗前平均眼压27.4±5.7mmHg;成功滤过泡32眼,成功率为82.1%。结膜下出血7眼,浅前房低眼压1眼,无伤口渗漏和脉络膜渗漏等并发症。结论：MMC结膜下注射联合针拨治疗小梁切除术后功能不良滤过泡是安全、简单、有效的方法。AIM： To evaluate the therapeutic effects of mitomycin C（ MMC） subconjuctival injection with needling revision on dysfunctional filtering blebs after trabeculectomy for glaucoma.METHODS： MMC 0. 1mL（ 0. 2mg /mL） subconjuctival injection with needling revision was performed on 39 eyes of 36 patients with dysfunctional filtering blebs 2 ~ 12 wk after trabeculectomy for glaucoma. An average of 1. 31 ±0. 58 times of treatment was performed. The intraocular pressure（ IOP）,blebs and complications were observed and follow up was conducted for 3mo.RESULTS： Three months after treatment,the mean IOP was 15. 8 ± 6. 6mmHg,significantly lower than that of before treatment（ 27. 4 ± 5. 7mmHg）. There were 32 eyes with successful filtering blebs,with the success rate of 82. 1%. Subconjuctiva hemorrhage occurred in 7 eyes,shallow anterior chamber and hypotony occurred in 1 eye,No such complications as leakage of the wound and choroidal effusion were observed during the follow up.CONCLUSION： MMC subconjuctival injection with needling revision is a safe,simple and effective method for dysfunctional filtering blebs after trabeculectomy.

关 键 词：丝裂霉素C 针拨 青光眼 小梁切除术 功能不良滤过泡 

分 类 号：R779.6[医药卫生—眼科]