硝酸银硅胶柱梯度洗脱法纯化桐酸甲酯  

Purification of Methyl Eleostearate by the AgNO_3-Silca Gel Column Gradient Elution Method

作　　者：刘芸双 傅伟昌[1] 

机构地区：[1]吉首大学林产化工工程湖南省重点实验室,湖南张家界427000

出　　处：《吉首大学学报（自然科学版）》2015年第1期52-56,共5页Journal of Jishou University(Natural Sciences Edition)

基　　金：湖南省科技厅科技计划项目(2010FJ4117);吉首大学校级课题(13JDY054)

摘　　要：以桐油和甲醇为原料,在NaOH催化下通过酯交换反应制备桐油酸甲酯,再采用硝酸银硅胶柱梯度洗脱法对反应产物进行分离纯化,获得桐酸甲酯.应用GC-MS,IR,UV,HPLC对反应产物进行分析检测和表征,桐酸甲酯纯度达95%,可用于合成桐酸单甘酯、甘二酯,以备深入研究桐酸及其甘油酯化物的生理活性.Fatty acid methyl esters of tung oil were synthesized by transesterifieation of tung oil and meth- anol with NaOH as catalyst. The AgNO3-silca gel column gradient elution method was used for the sepa ration of reaction product to obtain methyl eleostearate. The methyl eleostearate was characterized by GC-MS,IR,UV and HPLC. The purity of the final methyl eleostearate was found to be 95%. For further study of biological activities of eleostearic acid and its glyceryl ester compound, the methyl eleostearate can be used to synthesize monoglyceride and diglyceride of eleostearic acid.

关 键 词：桐酸甲酯 桐酸 桐油 制备 纯化 表征 

分 类 号：TQ646[化学工程—精细化工]