复方苦参注射液联合芬太尼透皮贴剂治疗老年食管癌患者疼痛的疗效观察  

Compound Kushen injecfion combined with Fentanyl transdermal patch for management of pain caused by senile esophageal

作　　者：冯献明[1] 陈小兵[2] 陈贝贝[2] 付方现[1] 刘红亮[3] 

机构地区：[1]林州市肿瘤医院,河南林州456500 [2]河南省肿瘤医院,郑州450000 [3]河南中医学院第一附属医院,郑州450000

出　　处：《医药论坛杂志》2015年第2期36-38,共3页Journal of Medical Forum

摘　　要：目的观察复方苦参注射液联合芬太尼透皮贴剂治疗老年食管癌疼痛的疗效和不良反应。方法选取60例老年食管癌疼痛的患者,以随机抽样法分为治疗组(30例)和对照组(30例),治疗组给予复方苦参注射液联合芬太尼透皮贴剂治疗,对照组单用芬太尼透皮贴治疗,观察两组治疗前后的疗效及不良反应。结果治疗组总缓解率为90.0%,对照组总缓解率为66.7%,两组总缓解率比较有统计学差异(P<0.05);治疗组第7、14d疼痛数字评分法评分分别为为(2.5±0.3)和(2.1±0.5)分,治疗组第7、14d疼痛数字评分法评分分别为为(2.7±0.2)和(2.4±0.3)分,两组第7、14d疼痛数字评分有显著的统计学差异。结论复方苦参注射液联合芬太尼透皮贴剂治疗老年食管癌患者疼痛疗效显著,能够明显改善患者的生活质量。Objective To observe the curative effect and side effect of the Compound Kushen injection and Fentanyl transdermal patch for the treatment of the pain of the senile esophageal cancer. Methods Totally 60 patients with the pain of senile esophageal cancer were randomized into the treatment group（ 30 cases） given Compound Kushen injection and Fentanyl transdermal patch,and the control group（ 30 cases） given Fentanyl transdermal patch to observe the curative effect and the side effect of two groups pre- therapy and post- treatment. Results Showed that the total effective rate was 90. 0% in the treatment group and 66. 7% in the control group,which indicated that there was a significant difference between them（ P〈0. 05）; The score of the Numerical Pain Rating Scale in the 7th,14 th,was（ 2. 5 ± 0. 3）and（ 2. 1 ± 0. 5） in the treatment group and（ 2. 7 ± 0. 2） and（ 2. 4 ± 0. 3） in the control group,which also indicated that there was a significant difference between them. Conclusion The therapeutic effect of the Compound Kushen injection and Fentanyl transdermal patch for the treatment of the pain of the senile esophageal cancer was distinct,can significantly improve the patient＇s quality of life.

关 键 词：复方苦参注射液 芬太尼透皮贴剂 老年食管癌 癌痛 

分 类 号：R735.1[医药卫生—肿瘤]