基于胃食管反流病的胃肠动力与脾虚实质探究  

Gastrointestinal motility and spleen deficiency in gastroesophageal reflux disease

作　　者：王红梅[1] 张立平[2] 陈丽如[2] 刘晶[1] 

机构地区：[1]北京中医药大学东方医院,北京100078 [2]北京中医药大学,北京100029

出　　处：《中国中西医结合消化杂志》2015年第3期196-198,共3页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

基　　金：国家自然科学基金项目(No:81273695);2014年北京中医药大学自主选题项目(No:2014-JYBZZ-JS-058)

摘　　要：现代医学认为胃食管反流病是由多种因素造成的消化道动力障碍性疾病;而中医认为其核心病机为脾虚。脾虚证是一种以多系统功能降低为特点,以胃肠道消化吸收功能低下、胃肠运动机能紊乱为主要表现的多系统功能障碍的病理状态。中西医对该病的病机和发病机制的认识高度一致提示脾虚和胃肠动力变化可能密切相关。本文以病带证,立足于胃食管反流病,致力发现可靠指标,从胃肠动力学的角度研究健脾法治疗胃食管反流病的作用机制和环节从而揭示脾虚实质。Modern medicine believes that gastroesophageal reflux disease（GERD）is a gastrointestinal motility disorder with multi-faceted pathogenic factors.While with Chinese medicine,spleen deficiency is deemed to play a core role in pathogenesis of GERD.From above,it is natural for us to make an association between gastrointestinal motility and spleen deficiency which is indicative of a hypo-functional state,manifested particularly as low digestive and absorptive capacity and disturbed gastrointestinal motility.This text is aimed to confirm the core role played by spleen deficiency in GERD from the standpoint of gastrointestinal motility,and therefore validate method of tonifying the spleen in treatment of GERD.

关 键 词：胃食管反流病 胃肠动力 脾虚 CAJAL间质细胞 

分 类 号：R573.9[医药卫生—消化系统]