肝性脑病院内管理概况  

Discussion on the issues about inhospital management of hepatic encephalopathy

作　　者：成璇[1,2] 吴战军 

机构地区：[1]山东省医学科学院 [2]济南大学医学与生命科学学院,山东济南250012 [3]解放军456医院,山东济南250031

出　　处：《实用医药杂志》2015年第3期234-237,共4页Practical Journal of Medicine & Pharmacy

摘　　要：肝性脑病(hepatic encephalopathy,HE)是一种由于急、慢性肝功能严重障碍或各种门静脉-体循环分流异常所致的,以代谢紊乱为基础的、轻重程度不同的神经精神异常综合征。HE的病理生理由多因素综合作用所致,其中最重要的是高氨血症和炎症协同作用引起星型胶质细胞肿胀、脑水肿。其发病机制及治疗方案及其效果、安全性仍在进一步探索中。笔者仅就其优化HE院内管理作一概述。Hepatic encephalopathy（HE） is a neuropsychiatric and functional syndrome ranging from altered mental status to deep coma,based on metabolic disorders,caused by acute or chronic liver failure or portal-systemic shunt. The pathogenesis is complex which centers with hyperammonia and inflammation together resulting in astrocyte swelling,then edema. The pathogenesis and therapy as wellas its efficacy,safety are still being studied.Here only how to optimate the inhospital management of HE is reviewed.

关 键 词：肝性脑病 院内管理 治疗 

分 类 号：R575.2[医药卫生—消化系统]