正畸扭转力对成人牙髓中IL-8活性影响的研究  

The study of the effect that orthodontic torsional force affected the quantity changes of IL-8 in adult dental pulp

作　　者：郭新星[1] 陈静[2] 张勇[1] 

机构地区：[1]济南市口腔医院正畸科,山东济南250001 [2]山东大学口腔医院,山东济南250012

出　　处：《临床口腔医学杂志》2015年第3期136-139,共4页Journal of Clinical Stomatology

基　　金：济南市科技卫生计划项目(2008-31)

摘　　要：目的:了解IL-8的活性变化,评价正畸扭转力对成人牙髓组织的影响。方法:选取矫治设计为拔除4个第一前磨牙成人正畸患者56例。根据上颌第一前磨牙采用交互牵引正畸扭转力值的不同分为4oz组、6oz组和8oz组,分别于加力1、2、3、4周后取出牙髓组织标本;对照组分别于实验组相同时间段内拔牙后,取出牙髓组织标本,应用光度酶联免疫分析法(ELISA)测定牙髓中IL-8的含量在矫治过程中的变化。结果:4oz组、6oz组、8oz组不同时段IL-8活性的比较均有所不同;加力1、2、3、4周组IL-8活性的比较均有所不同。结论:成人扭转牙纠正时,持续扭转力的大小是否会对牙髓活性产生损害,关键依据牙齿受到持续扭转力1-2周时牙髓状态,扭转力的大小需要低于8oz。Objective：To value the effects that orthodontic torsional force affects adult dental pulp＇s health status by observe the quantity changes of IL-8 in the dental pulp,and to realize that how orthodontic torsional force affects the or-thodontic tooth in order to improve the level of clinical orthodontic therapy. Method：Fifty six cases that four first premolar designed to be extracted were randomly selected from the orthodontic clinical patients. According to the value of the or-thodontic torsional force on upper jaw first premolar,all cases were divided into four ounce group,six ounce group and eight ounce group. The first premolar of the experimental patients was stressed by different orthodontic torsional force and then was extracted when the force had been activated for 1 weeks,2 weeks,3 weeks and 4 weeks.The first premolar in the control group was extracted respectively.The quantity of IL-8 from the dental pulp in different groups were detected by ELISA methods. Result：The multiple comparisons of IL-8 activity among four ounce group （αgroup）,six ounce group （βgroup） and eight ounce group （γgroup）are different.The multiple comparisons of IL-8 activity among the first week group ,second week group,third week group and fourth week group are different. Conclusion：From adult compare results of IL-8 activity, we could saw that in correcting adult torsional teeth whether continuous torsion force would cause damage to the dental pulp activity, the key was to see the dental pulp status which continued torsion force loaded for 1-2 weeks in the tooth.The tor-sional force needed less than 8 ounces.

关 键 词：扭转 牙髓 白细胞介素8(IL-8) 正畸 

分 类 号：R783.5[医药卫生—口腔医学]