Effect of Final Kissing Balloon Dilatation after One-stent Technique at Left-main Bifurcation： A Single Center Data  

作　　者：Zhan Gao Bo XU Yue-Jin Yang Shu-Bin Qiao Yong-Jian Wu Tao Chen Liang Xu Jin-Qing Yuan Jue Chen Xue-Wen Qin Min Yao Hai-8o Liu Shi-Jie You Ye-Lin Zhao Hong-Bing Yan Ji-Lin Chen Run-Lin Gao 

机构地区：[1]State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Beijing 100037, China [2]Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 210029, China

出　　处：《Chinese Medical Journal》2015年第6期733-739,共7页中华医学杂志（英文版）

摘　　要：Background:Whether final kissing balloon (FKB) dilatation after one-stent implantation at left-main (LM) bifurcation site remains unclear.Therefore,this large sample and long-term follow-up study comparatively assessed the impact of FKB in patients with unprotected LM disease treated with one-stent strategy.Methods:Total 1528 consecutive patients underwent LM percutaneous coronary intervention in one center from January 2004 to December 2010 were enrolled; among them,790 patients treated with one drug-eluting stent crossover LM to left anterior descending (LAD) with FKB (n =230) or no FKB (n =560) were comparatively analyzed.Primary outcome was the rate of major adverse cardiovascular events,defined as a composite of death,myocardial infarction (MI) and target vessel revascularization (TVR).Results:Overall,The prevalence of true bifurcation lesions,which included Medina classification (1,1,1),(1,0,1),or (0,1,1),was similar between-groups (non-FKB:37.0％ vs.FKB:39.6％,P =0.49).At mean 4 years follow-up,rates of major adverse cardiovascular events (non-FKB:10.0％ vs.FKB:7.8％,P =0.33),death,MI and TVR were not significantly different between-groups.In multivariate propensity-matched regression analysis,FKB was not an independent predictor of adverse outcomes.Conclusions:For patients treated with one-stent crossover LM to LAD,clinical outcomes appear similar between FKB and non-FKB strategy.Background:Whether final kissing balloon (FKB) dilatation after one-stent implantation at left-main (LM) bifurcation site remains unclear.Therefore,this large sample and long-term follow-up study comparatively assessed the impact of FKB in patients with unprotected LM disease treated with one-stent strategy.Methods:Total 1528 consecutive patients underwent LM percutaneous coronary intervention in one center from January 2004 to December 2010 were enrolled; among them,790 patients treated with one drug-eluting stent crossover LM to left anterior descending (LAD) with FKB (n =230) or no FKB (n =560) were comparatively analyzed.Primary outcome was the rate of major adverse cardiovascular events,defined as a composite of death,myocardial infarction (MI) and target vessel revascularization (TVR).Results:Overall,The prevalence of true bifurcation lesions,which included Medina classification (1,1,1),(1,0,1),or (0,1,1),was similar between-groups (non-FKB:37.0％ vs.FKB:39.6％,P =0.49).At mean 4 years follow-up,rates of major adverse cardiovascular events (non-FKB:10.0％ vs.FKB:7.8％,P =0.33),death,MI and TVR were not significantly different between-groups.In multivariate propensity-matched regression analysis,FKB was not an independent predictor of adverse outcomes.Conclusions:For patients treated with one-stent crossover LM to LAD,clinical outcomes appear similar between FKB and non-FKB strategy.

关 键 词：ANGIOPLASTY BALLOON BIFURCATION Percutaneous Coronary ANGIOPLASTY Unprotected Left-main 

分 类 号：R[医药卫生]