单眼远视性弱视儿童P-VEP检查的相关研究与临床分析  

Related research and clinical analysis of P-VEP in 63 cases monocular hyperopic refractive amblyopic children

作　　者：周妍丽[1] 钱志刚[1] 陈建平[1] 

机构地区：[1]湖北省文理学院附属医院襄阳市中心医院眼科,湖北襄阳441021

出　　处：《中国中医眼科杂志》2014年第6期432-434,共3页China Journal of Chinese Ophthalmology

摘　　要：目的探讨远视屈光不正性弱视儿童弱视的外周发病机制。方法 2011年11月至2013年9月在我院就诊的单眼远视屈光不正性弱视儿童63例(63只眼)和正常儿童30例(60只眼),按相关标准分为5组:轻度远视性弱视眼组(A组)及对侧健眼组(B组)、中度远视性弱视眼组(C组)及对侧健眼组(D组)、正常儿童眼组(E组)。予P-VEP检查分析各组P100波的潜伏期和振幅情况。结果 2组弱视眼P100潜伏期较对侧健眼及正常儿童眼延长(P<0.01),振幅较正常儿童眼降低(P<0.05),并略低于对侧健眼(P=0.02),轻、中度弱视眼的潜伏期及振幅差异无统计学意义(P>0.05);2组弱视对侧健眼的潜伏期与正常儿童眼数值接近(P>0.05),而振幅均低于正常儿童眼(P=0.01),2组对侧健眼的潜伏期及振幅差异均无统计学意义(P>0.05)。结论单眼远视性弱视儿童的弱视眼的P100潜伏期延迟、振幅下降,提示弱视眼的视神经受累,支持了远视屈光不正性弱视的外周发病机制理论。OBJECTIVE To study the optic nerve of monocular hyperopic refractive amblyopic children using pattern visual evoked potential to investigate the peripheral incidence mechanism of monocular hyperopic refractive amblyopic children. METHODS We did P-VEP examination for the children who came to the clinic of ophthalmology department from November 2011 to September 2013. The children included monocular hyperopic refractive amblyopic children （63 cases 63 eyes） and normal children （30 cases 60 eyes）. We put these children into five groups according to relevant standards and measure their Pl0o latency and amplitude. RESULTS The mild and moderate hyperopic refractive amblyopic group： the amblyopic eye＇ s Plao latency comparing with the healthy eye and the normal children group had remarkable statistical significance （P〈0.01）. The healthy eye＇s Pl00 latency comparing with the normal children group had no significance （P〉0.05）. The healthy eye＇ s P100 amplitude comparing with the amhlyopic eye and the normal children group had statistical significance （P〈0.05）. The amblyopic eye＇s P,00 amplitude comparing with the normal children group had remarkable statistical significance （P〈0.01）. Comparing the mild hyperopic refractive amblyopic group and the moderate hyperopic refractive amblyopic group： Compare both the amblyopic eyes and the healthy eyes＇ P100 latency and amplitude had no significance （P〉0.05）. Whether the amblyopic eye of mild hyperopic refractive amblyopic group or the amblyopic eye of moderate hyperopic refractive amblyopic group comparing with the healthy eye, P10o latency have remarkable statistical significance （P〈 0.01 ） and P,00 amplitude had statistical significance （P〈0.05）. CONCLUSIONS Through P-VEP examination of monocular hyperopic refractive amblyopic children, the amblyopic eye＇s P100 latency delaying and P100 amplitude falling were found, and these pointed out abnormal of optic nerve. These confirmed the theories about peripheral path

关 键 词：远视 屈光不正性弱视 P-VEP 潜时 振幅 

分 类 号：R777.44[医药卫生—眼科]