福建省功能性消化不良患者的临床特点调查  

The clinical characteristics of functional dyspepsia in Fujian province

作　　者：陈爱锦[1,2,3] 王承党[1,2,3] 李文清[1,2,3] 陆岽[1,2,3] 丁健[1,2,3] 庄则豪[1,2,3] 吴婷[1,2,3] 陈玉丽[1,2,3] 

机构地区：[1]福建医科大学附属第一医院消化内科,福建福州350005 [2]福建医科大学附属第一医院消化内镜中心,福建福州350005 [3]福建医科大学附属第一医院消化系疾病研究室,福建福州350005

出　　处：《胃肠病学和肝病学杂志》2015年第3期325-328,共4页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的了解福建省三级医院消化内科门诊功能性消化不良(functional dyspepsia,FD)患者的临床症状特点。方法问卷调查2011年9月-2012年4月在福建省三级医院消化内科就诊、符合罗马Ⅲ诊断标准的FD患者的临床特征。结果纳入研究的FD患者1 075例,男女比例为1∶1.42,平均年龄(43.8±12.8)岁,中位病程2.5年。其中,上腹痛综合征(EPS)617例(57.40%)、餐后不适综合征(PDS)458例(42.60%);常见的上消化道症状为:上腹痛702例(65.30%)、餐后饱胀626例(58.23%)、腹部不适609例(56.65%)、腹胀593例(55.16%)、嗳气566例(52.65%)等;14.70%有疾病重叠,436例(40.56%)报告"睡眠不好",342例(31.81%)有"情绪不好",319例(29.67%)认为"影响生活";818例(76.09%)认为出现症状之前有"诱发因素",如:过度劳累(31.81%)、受凉255例(23.72%)、精神紧张210例(19.53%)等。83例(13.15%)女性患者在月经期或月经前期FD症状加重。结论福建省三级医院消化科门诊FD以EPS多见,对睡眠、情绪等影响比较大,大部分患者可以找到"诱发因素"。因此,在临床治疗中调整生活方式与药物治疗一样重要。Objective To investigate the symptom characteristics of functional dyspepsia （FD） in tertiary hospitals of Fujian Province. Methods FD outpatients fulfilled the Rome II1 criteria from tertiary hospitals in Fujian Province were investigated with a questionnaire including symptom scores and frequency. Results One thousand and seventy-five outpatients with a mean age of （43.8 ：t： 12.8） years old and a median course of 2.5 years were included. Sixty hundred and seventeen （57.40%） patients were diagnosed with epigastric pain syndrome （EPS） and 458 cases （42.60%） were postprandial distress syndrome （PDS）. The common symptoms were epigastric pain （102, 65.30% ） , postprandial full- ness （626, 58.23% ）, abdominal discomfort （609, 56.65% ）, abdominal distention （593, 55.16% ）, and belching （566, 52.65% ）. One hundred and fifty-eight （14.70%） patients overlapped gastroesophageal reflux disease or irrita- ble bowel syndrome, and 76. 090/0 patients had some causative factors, such as fatigue, cold, psychentonia. Eighty three （83, 13.15% ） femal patients reported their symptomes worse before or during the menstrual period. Conclusion The most common subtype of FD was EPS, which may induce dyssomnia and enotional disorder. And some causative factors may lead to the onset of sympotoms. Thus. lifestyle changes may be as important as medicine administration in the management of FD.

关 键 词：功能性消化不良 症状学 诱发因素 临床特点 

分 类 号：R735.2[医药卫生—肿瘤]