认知障碍简明评价量表和阿尔茨海默病相关症状量表对高龄人群认知能力评价的初步比较研究  

A preliminary study to compare the capacity of Cog-12 scale to assess the cognitive function of the 80-year elder or more with ROSA

作　　者：潘晓东[1] 周辰[1] 徐俊[1] 何一然[1] 尹冬华[1] 张长春[1] 顾小花[1] 

机构地区：[1]江苏省老年医学研究所,南京210024

出　　处：《中华临床医师杂志（电子版）》2015年第7期12-15,共4页Chinese Journal of Clinicians(Electronic Edition)

基　　金：江苏省干部保健专项资金科研课题(GB13-057);国家自然科学基金资助项目(30700248;81271211);江苏省科技支撑计划(社会发展)(BE2011614)

摘　　要：目的比较认知障碍简明评价量表（Cog-12）和阿尔茨海默病相关表现量表（ROSA）对≥80岁的老年人群认知功能评价的差异。方法选择80岁以上高龄老人,按照认知功能水平分3组：正常对照（NC组）38例;遗忘型轻度认知障碍（a MCI）患者31例;痴呆患者32例。每组完成Cog-12、ROSA及蒙特利尔认知量表（Mo CA）、简明智能精神量表（MMSE）等量表评定,并对94例患者在初诊的1～3周之间进行Cog-12的复测。结果 Cog-12的复测信度Pearson系数为0.987,内部信度克朗巴哈α系数为0.950。与ROSA、Mo CA、MMSE的共时效度（Pearson系数）分别为-0.883、-0.820、-0.840。Cog-12对照料者负担的评价甚至优于ROSA。结论 Cog-12是一个方便的多维度认知功能筛查工具,可以有效地评价高龄老年人群的认知能力,其评价效果与ROSA相似。Objective The aim of this study was to compare the difference between the Cog-12 scale and ROSA（The Relevant Outcome Scale for Alzheimer＇s Disease） to assess the cognitive function of the individuals over 80 years old. Methods Total 101 elders were enrolled in this research. According to the level of cognitive, patients were sent to three group including normal control group（NC）, a MCI group and dementia group. Thirty-eight individuals were diagnosed as normal and thirty-one people were considered as MCI patients. The neuropsychological tests such as the Cog-12 scale, ROSA, the Montreal cognitive assessment（Mo CA） and the Mini Mental Status Examination（MMSE） were completed. There were 94 patients retested Cog-12 in 3 weeks. Results The test-retest reliability of Cog-12 was excellent with the pearson coefficient got 0.987. The Cronbach＇s α coefficient was 0.950. The Cog-12 showed good concurrent validity because the pearson correlation coefficients with ROSA, Mo CA and MMSE were-0. 883,-0.820 and-0.840. In terms of estimating the caregiver burden, Cog-12 was even better than ROSA. Conclusions Cog-12 scale is a useful, easy and multidomain tool in cognitive function assessment. The effectiveness of Cog-12 to evaluate the cognitive function is same as ROSA in the elder.

关 键 词：Cog-12量表 ROSA 认知功能 

分 类 号：R749.16[医药卫生—神经病学与精神病学]