耳鼻喉科患者多药耐药菌感染的相关研究  

Study on multi-drug resistant bacterial infections in otorhinolaryngological patients

作　　者：冯涛[1] 牟雪萍[1] 张琴琴[1] 王卫国[1] 于海洋[1] 

机构地区：[1]淄博市中心医院北院区耳科,山东淄博255031

出　　处：《中华医院感染学杂志》2015年第7期1527-1529,共3页Chinese Journal of Nosocomiology

基　　金：山东省科技厅研究基金资助项目(2013-0768X)

摘　　要：目的观察耳鼻喉科科患者感染多药耐药菌的分布特征以及影响因素,为临床感染的控制提供相关的依据。方法选取2011年3月-2013年5月耳鼻喉科收治的感染性疾病患者共125例,回顾性分析其感染多药耐药菌的例次率,通过医院感染的统计分析对耐药菌株种类和特征及检出率进行统计,采用SPSS19.0进行统计处理。结果耳鼻喉科患者医院感染多药耐药菌主要以革兰阴性菌为主,占66.67%,革兰阳性菌占33.33%,同时多发生于头颈部恶性肿瘤围手术期,感染前抗菌药物使用时间<7d者较使用时间>7d者检出率低,对比差异有统计学意义(P<0.05)。结论在耳鼻喉科感染疾病患者的预防和控制过程中,要对其感染多药耐药菌的种类和耐药性进行检测与分析,加强对标本的培养检查和药敏试验,从而在临床上更加合理的使用抗菌药物,降低耳鼻喉科多药耐药菌感染率。OBJECTIVE To observe the distribution of multi-drug resistant bacteria in otorhinolaryngological patients and the influencing factors of infections,so as to provide the basis for the control of clinical infections.METHODS A total of 125 cases of patients with infectious disease from Mar.2011 to May 2013 in the otorhinolaryngological department were selected,and their case-time medical data of multi-drug resistant bacterial infections were retrospectively analyzed.The resistant bacteria detection rate,the types and characteristics were summarized through the statistical analysis of nosocomial infections.The software SPSS19.0was used for statistical analysis.RESULTS The main multi-drug resistant bacteria were gram-negative bacteria accounting for 66.67% and grampositive bacteria accounting for 33.33%,and mostly occurred in the operation period of head and neck malignant tumor.The detective rate was signifiontly lower in patients with antibiotic usage time7dbefore infections than in those with antibiotic usage time〉7d（P〈0.05）.CONCLUSIONIn the prevention and control of infections in otorhinolaryngological patients,clinicians should detect and analyze the types and drug resistance of multi-drug resistant bacteria,strengthen the cultivation and inspection of specimens and drug sensitivity test,so as to clinically use antibiotics more reasonably and reduce the incidence of otorhinolaryngological multi-drug resistant bacterial infections.

关 键 词：耳鼻喉科 多药耐药菌 医院感染 分类及特征 

分 类 号：R378[医药卫生—病原生物学]