The seeming paradox of adenosine receptors as targets for the treatment of Alzheimer's disease: agonists or antagonists?  

作　　者：Rubina Marzagalli Alessandro Castorina 

机构地区：[1]Department of Biomedical Sciences and Biotechnologies, Section of Human Anatomy and Histology, University of Catania

出　　处：《Neural Regeneration Research》2015年第2期205-207,共3页中国神经再生研究（英文版）

摘　　要：Alzheimer＇s disease （AD） is the most common neurodegenerative disorder, and its incidence is relatively high among elderly people, affecting about 1-2% of the population between 60-65 years old and rising dramatically （about 30%） in people aged 80 years or older （Selkoe, 2002）. Nowadays, considering the increasing mean lifespan of populations in developed countries, the disease is becoming more and more a health concern, and the search for an effective cure has turned into＂a real need＂.Alzheimer＇s disease （AD） is the most common neurodegenerative disorder, and its incidence is relatively high among elderly people, affecting about 1-2% of the population between 60-65 years old and rising dramatically （about 30%） in people aged 80 years or older （Selkoe, 2002）. Nowadays, considering the increasing mean lifespan of populations in developed countries, the disease is becoming more and more a health concern, and the search for an effective cure has turned into＂a real need＂.

关 键 词：The seeming paradox of adenosine receptors as targets for the treatment of Alzheimer’s disease agonists or antagonists 

分 类 号：R749.16[医药卫生—神经病学与精神病学]