急性脑卒中患者红细胞分布宽度对预后的影响  

The influence of red blood cell distribution width on the prognosis of patients with acute cerebral stroke

作　　者：王盟[1] 刘力松[1] 华琦[1] 庞蓓蕾[1] 李碧汐 周亚群[1] 

机构地区：[1]首都医科大学宣武医院心脏科,北京100053

出　　处：《中国临床保健杂志》2015年第2期128-131,I0001,共5页Chinese Journal of Clinical Healthcare

摘　　要：目的探讨急性脑卒中患者红细胞分布宽度(RDW)对不良预后的影响。方法回顾性分析264例首次诊断为急性脑卒中患者的临床资料,随访发病后6个月,其中男性225例,女性39例,改良的Rankin量表评分(MRS)>2患者69例和MRS≤2患者195例,MRS=6患者6例和MRS<6患者258例,分别进行比较。结果 (1)RDW与MRS评分呈正相关(r=0.328,P<0.01)。(2)男性与女性的RDW分别为(12.68±0.78比13.53±2.49),对RDW与性别进行秩和检验,两组间差异无统计学意义。对MRS评分与性别进行秩和检验,两组间差异有统计学意义(P<0.05)。(3)69例患者在急性脑卒中后的6个月出现预后不良(MRS>2),预后不良的RDW更高(13.46±1.33比12.57±1.11),秩和检验示P<0.01。6例患者在急性脑卒中后的6个月出现死亡,死亡患者的RDW略高(13.23±1.32比12.79±1.23),但差异无统计学意义。(4)二元Logistic回归分析显示,糖尿病(P=0.014)、年龄(P=0.042)、RDW(P=0.000)是中青年急性脑卒中的独立危险因素。结论急性脑卒中患者RDW是预后不良的一项独立危险因素。Objectives To investigate the effect of red blood cell distribution width on the clinical outcomes and mortality of patients with acute cerebral stroke.Methods A total of 264 patients with atherosclerotic acute cerebral infarction admitted in the department of neurology in Xuanwu Hospital,Capital Medical University from Febrary2011 to January 2014 were analyzed retrospectively.The follow-up time was 6 months after onset There were 225 cases in male group and 39 cases in female group,and there were 69 cases in MRS 2 group,195 cases in MRS≤2 group,and 6 cases in MRS = 6 group,258 cases in MRS 6 group.The data were compared among groups.Results（1） Linear correlation analysis showed that RDW was positively correlated with MRS.（2） The male and female RDW were（12.68 ± 0.78 vs.13.53 ± 2.49） respectively and there were no significant difference between the two groups on the rank sum test.There was significant difference in MRS score and gender between the two groups（P 0.05）.（3）69 patients at 6 months after acute strokehad poor prognosis（MRS 2）,whose red cell distribution width werehigher（13.46 ± 1.33 vs.12.57 ± 1.11） than that of MRS≤2（P 0.01）,6 patients were died 6th month after acute stroke,whose red cell distribution width of death withhigher（13.23 ± 1.32 vs.12.79 ± 1.23） than that of survival.（4） Binary Logistic regression analysis showed that,diabetes,age,RDW were an independent risk factors of acute stroke in young patients with acute cerebral stroke.Conclusion The red cell distribution width is an independent risk factors in young patients with acute cerebral stroke.

关 键 词：卒中 红细胞 异常 预后 危险因素 

分 类 号：R743.33[医药卫生—神经病学与精神病学]