曲线牵张成骨的初步实验研究  

A primary study of curvilinear distraction osteogenesis

作　　者：张国华[1,2] 商洪涛 郭宇轩 刘翔宇 何黎升[1] 

机构地区：[1]第四军医大学口腔医院口腔颌面外科.军事口腔医学国家重点实验室,西安710032 [2]中国人民解放军庐山疗养院

出　　处：《实用口腔医学杂志》2015年第2期153-156,共4页Journal of Practical Stomatology

基　　金：国家科学自然科学基金(编号:81070872)

摘　　要：目的:探讨下颌骨弧线式牵张成骨修复部分下颌骨缺损的可行性。方法:以3只大型成年犬建立实验动物模型,制造下颌骨节段性弧形缺损,植入自行研发的内置弧线式骨牵张器,牵引间歇期7 d,牵引速度0.5 mm×2次/d,固定期3个月,共牵引约30 mm,采用大体观察、X线以及组织学观察其成骨特点。结果:实验过程中无感染等不良并发症,球形传力内置弧线式骨牵张器固位始终良好,大体观察可见骨呈现弧形愈合良好,X线影像显示:牵引结束时,骨移动盘实现显著的改向、内旋的曲线移动,与远端下颌骨呈弧线连接,HE染色显示出明显的新骨形成带。结论:球形挤压传力内置弧线式骨牵张器能够实现下颌骨后段弧线式牵张成骨。Objective：To seek the possibility of using internally installed curved mandibular distractor to repair the partial mandibular curved defect.Methods：A curved mandibular defect was sectioned in each of 3 adult dogs.The distractor designed by our own group based on the steel ball conducted force was implanted.After 7 days of latency,the distraction was performed at the rate of 0.5 mm ＆#215; 2 times per day,followed by 3 months consolidation period.The osteogenesis was evaluated by general observation,X-ray examination and HE staining.Results：No complication was observed after operation and during distraction.The new bone healed well into a curved shape.The X-ray examination revealed that the transport disc moved along with the predesigned rail curve.HE staining clearly showed neo bone formulation zone between the mature trabecular and connective tissue.Conclusion：The internal distractor based on the steel ball conducted force can realize the curved distraction osteogenesis of posteriormandibular.

关 键 词：下颌骨 牵张成骨 弧形牵张器 

分 类 号：R782[医药卫生—口腔医学]