高强度聚焦超声对恶性肿瘤患者血浆D-二聚体的影响  

The influence of high intensity focused ultrasound on plasma D- dimer in patients with malignant tumor

作　　者：肖元元[1] 赵华新[1] 赵瑜[1] 茅伟[1] 刘竹青[1] 崔然[1] 许青[1] 

机构地区：[1]同济大学附属上海市第十人民医院肿瘤科,上海200072

出　　处：《现代肿瘤医学》2015年第7期989-991,共3页Journal of Modern Oncology

基　　金：国家自然科学基金(编号:30872591);上海市科学技术委员会科研计划项目课题(编号:11411950602)

摘　　要：目的:探究高强度聚焦超声对肿瘤患者血浆D-二聚体水平的影响。方法:分析35例经高强度聚焦超声治疗的恶性肿瘤患者,检测治疗前后患者血浆D-二聚体水平,分析比较治疗前后浓度变化。结果:经高强度聚焦超声治疗的35例恶性肿瘤患者的血浆D-二聚体水平较治疗前降低,差异有统计学意义。60岁及以上的恶性肿瘤患者经高强度聚焦超声治疗后血浆D-二聚体水平有所下降,高强度聚焦超声可明显降低临床Ⅳ期的恶性肿瘤患者的血浆D-二聚体水平,治疗前后的D-二聚体水平均具有显著性差异。结论:高强度聚焦超声可降低恶性肿瘤患者血浆D-二聚体水平。Objective： To observe the effect on plasma D- dimer levels in patients with maliglancy treated by high intensity focused ultrasound. Methods： Analyzing 35 cases of malignant tumor patients treated by high intensity focused ultrasound,and detecting their plasma D- dimer levels and comparing the concentration changes before and after treatment. Results： Plasma D- dimer levels of 35 malignant tumor patients with high intensity focused ultrasound treatment were lower than the levels before therapy,and the difference was statistically significant. The plasma D- dimer levels were significantly decreased in patients over 60 years old with malignant tumor treated by high intensity focused ultrasound. High intensity focused ultrasound could significantly reduce the plasma D- dimer levels of malignant tumor patients in clinical stage Ⅳ. The D- dimer levels before and after treatment showed significant differences. Conclusion： High intensity focused ultrasound could reduce plasma D- dimer levels of malignant tumor patient.

关 键 词：高强度聚焦超声 恶性肿瘤 D-二聚体 

分 类 号：R730.58[医药卫生—肿瘤]