TACE联合PSE在原发性肝癌并脾亢治疗中的应用  

Application of TACE combined with PSE in the treatment of primary liver cancer and hypersplenism

作　　者：刘杰[1] 刘鸿章[1] 周荣林[1] 段文都 李根[1] 

机构地区：[1]保定市第三医院,河北保定071000

出　　处：《现代肿瘤医学》2015年第8期1097-1099,共3页Journal of Modern Oncology

摘　　要：目的:探讨原发性肝癌行TACE联合不同程度PSE对术后血常规及肝功能部分化验指标的影响。方法:2014年4月至2014年6月对本院原发性肝癌伴脾功能亢进行TACE联合PSE治疗的患者45例,按照脾栓塞比例分为:脾栓塞程度<50%(A组)、50%-60%(B组),术前及术后每周复查外周血WBC、PLT、AST、ALT、TBI至术后第8周,并进行Child分级。结果:A、B两组患者术后外周血中WBC、PLT计数均较术前有所升高,B组升高更明显,在随访末期A组明显呈下降趋势;A、B两组术前术后肝功能无明显变化。结论:在TACE联合PSE治疗中,脾栓塞比例是影响外周血WBC、PLT的重要因素;不同脾栓塞比例对肝功能无明显影响,高比例脾栓塞可加重栓塞后反应。Objective：To investigate the effect of primary liver cancer treat by transcatheter arterial chemoemboli- zation （ TACE ） combined with partial splenic embolization （ PSE ）. Methods ： All 45 case of primary liver cancer pa- tients with splenic function treat by TACE combined with PSE were divided in to splenic embolization degree 〈 50% （ group A） ,50% - 60% （ group B ） , preoperative and postoperative weekly review peripheral WBC, PLT, AST, ALT, TBI to 8 weeks after surgery. Results：A, B two groups postoperative WBC and PLT count in peripheral blood was in- creased, compared with preoperative group B increased more obviously. A, B two groups of preoperative postoperative liver function has no obvious change. Conclusion ： Proportion of splenic embolization is one of the important factors af- fecting peripheral WBC, PLT. Different splenic embolization pereentage had no obvious effect on liver function, high proportion of splenic embolization can increase reaction after embolization.

关 键 词：TACE PSE 原发性肝癌 脾功能亢进 血常规 肝功能 

分 类 号：R735.7[医药卫生—肿瘤]