枸橼酸坦度螺酮胶囊治疗神经性头痛50例疗效观察  

Efficacy Observation on the Tandospirone Citrate Capsules for 50 Cases of Nervous Headache

作　　者：储新娟[1] 肖伟忠[1] 李清华[1] 沈燕[1] 潘丹红[1] 

机构地区：[1]复旦大学附属上海市浦东医院神经内科,上海201399

出　　处：《现代生物医学进展》2015年第9期1718-1720,共3页Progress in Modern Biomedicine

摘　　要：目的:观察枸橼酸坦度螺酮胶囊治疗神经性头痛的临床效果。方法:将100例神经性头痛患者随机分为治疗组和对照组各50例。对照组给予氨酚羟考酮片、甲钴胺片治疗,治疗组在对照组的基础上加用枸橼酸坦度螺酮胶囊,对比两组临床疗效及视觉模拟评分(VAS评分)。结果:治疗后两组患者VAS评分均显著减小,其中治疗组相比对照组降低更明显,差异均有统计学意义(均P<0.05);治疗组患者总有效率为88.0%(44/50)显著高于对照的68.0%(34/50),差异具有统计学差异(P<0.05);两组患者均无明显不良反应。结论:枸橼酸坦度螺酮胶囊联合氨酚羟考酮片、甲钴胺片治疗神经性头痛疗效优良,能有效缓解痛疼程度,副作用小。Objective： To investigate the therapeutic effect of Tandospirone Citrate Capsules in the treatment nervous headache. Methods： 100 patients with nervous headache were randomly divided into the control group who were treated with Oxycodone and Acetaminophen Tablets and the treatment group who were given Tandospirone Citrate Capsule besides Oxycodone and Acetaminophen Tablets. There were 50 cases in each group. Visual analogue scale （VAS） and clinical curative effect of the two groups were compared. Results： After treatment, the VAS scores of two groups of patients were significantly decreased, and the sores for the treatment group decreased more significantly compared with that of the control group, the differences were statistically significant （all P〈0.05）; The total effective rate in the treatment group was 88.0%（44/50）, significantly higher than 68%（34/50） of the control group, the differences was statistically significant （P〈0.05）; There was no obvious adverse reactions in the two groups. Conclusion： Tandospirone Citrate Capsules with Oxycodone and Acetaminophen Tablets can effectively ease the pain with few side effect, it has good therapeutic effect in treatment of nervous headache.

关 键 词：枸橼酸坦度螺酮胶囊 神经性头痛 疗效 

分 类 号：R747[医药卫生—神经病学与精神病学]