原发性肝脏淋巴瘤伴慢性乙型肝炎的诊疗探讨(附3例临床报道)  

Primary liver lymphoma in three patients with chronic hepatitis B infection

作　　者：杨新伟[1] 陈骏毅[2] 杨珏[1] 张宝华[1] 沈锋[1] 吴孟超[1] 

机构地区：[1]第二军医大学东方肝胆外科医院腹腔镜科,上海200438 [2]上海市第一人民医院分院普通外科,上海200081

出　　处：《肝胆外科杂志》2015年第1期21-24,共4页Journal of Hepatobiliary Surgery

摘　　要：原发性肝脏淋巴瘤是一种罕见的恶性肿瘤,由于缺乏特异性的症状和影像学特点,术前确诊较为困难。据报道在慢性丙型肝炎患者中发病率较高,但有关原发性肝脏淋巴瘤结合并慢性乙型肝炎的临床报道较少。对我院收治的3例原发性肝脏淋巴瘤合并慢性乙型肝炎病例进行总结报道,多数患者出现腹部疼痛症状,影像学多表现为孤立性肝脏肿块,肿瘤多发的情况比较少见,弥散大B细胞型淋巴瘤是最常见的组织类型。采用手术联合术后化疗的综合治疗效果较好。Primary liver lymphoma is extremely rare. The diagnosis depends on the physician＇ s suspicions and histological examination. The rarity of the disease causes problems in diagnosis and management. It has been reported to occur with increased frequency in patients with chronic hepatitis C infection. However, there is rare report about the management and relationship between primary liver lymphoma and chronic hepatitis B infection. Most patients with PHL present with abdominal pain, constitutional symptoms and have hepatomegaly on examination. Imaging studies reveal solitary, or less often, multiple masses in the liver. The predominant histology is B-cell lymphoma, most commonly diffuse large cell type. The surgery followed by adjuvant chemotherapy should be considered to prevent disease recurrence with better prognosis.

关 键 词：原发性肝脏淋巴瘤 慢性乙型肝炎 手术 化疗 预后 

分 类 号：R735.7[医药卫生—肿瘤]