肝纤维化无创性诊断技术的临床应用  

Clinical application of noninvasive diagnosis of liver fibrosis

作　　者：朱传龙[1] 王坤[1] 高人焘[1] 

机构地区：[1]安徽医科大学安徽省立医院感染病科,合肥230001

出　　处：《临床肝胆病杂志》2015年第3期332-336,共5页Journal of Clinical Hepatology

基　　金：国家自然科学基金资助项目(81271713);安徽省第五批优秀青年科技基金滚动支持项目(11308085JGD09)

摘　　要：肝纤维化是各种病因引起的慢性肝病的共同转归。目前,肝活组织检查是肝纤维化诊断的"金标准",但其有一定的创伤性及局限性,因此无创评估肝纤维化技术得到了推行和发展。主要从临床表现、血清学及影像学等方面介绍了无创性诊断肝纤维化技术及其应用,指出了这些无创性诊断技术的临床价值,并针对目前无创诊断肝纤维化在临床研究的进展及其局限性进行了探讨。Hepatic fibrosis is the common outcome of chronic liver diseases of various causes. At present,liver biopsy is the ＂gold standard＂for the diagnosis of liver fibrosis,but it has limitations and is invasive,which leads to the development of noninvasive assessment of liver fibrosis. The article mainly introduces the technology and application of noninvasive diagnosis of liver fibrosis from the aspects of clinical manifestation,serology,and radiology. It has pointed out the clinical value of these noninvasive diagnosis techniques,and it discusses the progress in clinical research and its limitations for noninvasive diagnosis of liver fibrosis.

关 键 词：肝硬化 诊断 血清学试验 放射摄影影像解释 计算机辅助 

分 类 号：R575.2[医药卫生—消化系统]