斯普林联合放射治疗对局部晚期非小细胞肺癌免疫功能的影响  

The influences of spring combined with radiotherapy on the immune function of the patients with local advanced non-small cell lung cancer

作　　者：祝明池[1] 王丽丽[1] 

机构地区：[1]山东省日照市山东大学齐鲁医院日照分院肿瘤科,日照276800

出　　处：《中国肿瘤临床与康复》2015年第4期397-399,共3页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的分析斯普林治疗局部晚期非小细胞肺癌(NSCLC)的疗效及对免疫功能的影响。方法选取100例局部晚期NSCLC患者,随机分为观察组和对照组,每组50例。对照组给予放射治疗,观察组给予放射治疗联合斯普林治疗。对两组患者的临床疗效和T细胞亚群情况进行比较。结果观察组患者的生活质量指标、临床总有效率和治疗后1年生存率优于对照组(P<0.05)。观察组患者的T细胞亚群呈现免疫功能增强的趋势,对照组患者则呈反向变化。结论斯普林治疗局部晚期NSCLC的疗效显著,可提高患者生活质量和生存率,改善患者免疫功能。Objective s To analyze curative effects of Spring in the treatment of the patients with local advanced non-small cell lung cancer（ NSCLC） and its influences on the immune function. Methods100 patients with local advanced NSCLC were selected and randomly divided into the observation group and the control group. 50 cases were included into each group. The patients in the control group were treated with radiotherapy treatment,while the patients in the observation group were treated with radiotherapy combined with Spring therapy. The curative effects and T cell subsets of the patients of the two groups were observed and compared. Results The life quality indexes,the clinical total effective rate,and the 1 year survival rate of the patients in the observation group were significantly higher than those of the control group（ P〈0. 05）. T cell subsets condition of the patients in the observation group presented an increasing immune function,while that of the patients in the control group showed a reverse change. Conclusion The curative effects of applying Spring to the treatment of local advanced NSCLC are significant. The application can improve the life quality,the survival rate,and the immune function of the patients.

关 键 词：癌 非小细胞肺 放射疗法 斯普林 免疫功能 疗效观察 

分 类 号：R734.2[医药卫生—肿瘤]