利用图像引导放疗技术评价腘窝固定法减少子宫颈癌术后放疗摆位误差的研究  被引量:3

The evaluation of popliteal fossa fixed method to reduce setup errors for postoperative cervical cancer via CBCT

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作  者:彭逊[1] 甘勇[1] 林珠[1] 林正忠[1] 林浩[1] 陈泽伟[1] 

机构地区:[1]汕头大学医学院附属肿瘤医院放疗科,515031

出  处:《肿瘤研究与临床》2015年第3期179-182,共4页Cancer Research and Clinic

基  金:汕头市科学技术局社会发展攻关项目(2014-62)

摘  要:目的 利用TrueBeam直线加速器图像引导放疗技术(CBCT)校验腘窝固定法减少子宫颈癌摆位误差的价值,寻找适合术后精确放疗的体位固定方式.方法 30例子宫颈癌术后患者随机分成两组,A组采用梯形固定器腘窝固定,B组采用传统真空垫体部固定,通过CBCT记录轴向摆位误差及旋转误差数值,采用Stroom扩边公式计算两种固定方式计划靶区(PTV)外扩值,比较不同固定法摆位误差及稳定性,比较危及正常器官照射体积差异.结果 A、B组X轴向误差分别为(0.19±0.14)cm、(0.24±0.19)cm(P=0.03),Y轴向分别为(0.17±0.12)cm、(0.25±0.21)cm(P=O.02),Z轴向分别为(0.13±0.11)cm、(0.22±0.18)cm(P=0.01),旋转误差分别为(0.05±0.02)°、(0.5±0.21)°(P=0.00),A、B两组在X轴向PFV外扩值分别为0.56、0.73 cm,Y轴向分别为0.51、0.78 cm,Z轴向分别为0.40、0.67 cm,PTV体积分别为(1 167±271)mm^3、(1 379±297)mm^3,A、B组骨盆、小肠、膀胱、直肠照射体积分别为(84± 12)mm^3比(130±17)mm^3、(81±51)mm^3比(117 ±64)mm^3、(62±40) mm^3比(75±47) mm^3、(21±16)mm^3比(31 ±21)mm^3.结论 腘窝固定法可减少子宫颈癌术后外照射放疗摆位误差,提高稳定性,减少危及正常器官的照射体积,更适合精确放疗的应用.Objective To evaluate the effect of popliteal fossa fixed method to reduce the setup errors in patients with postoperative cervical carcinoma by CBCT of TrueBeam Linear accelerator.Methods 30 cases of postoperative cervical cancer patients were randomly divided into two groups,group A with popliteal fossa fixed method by trapezoidal fixation,group B with traditional vacuum pad fixation.CBCT was used to record both setup errors and rotational errors,Stroom extension formula was used to calculate the PTV expansion value coming from the two different fixation methods.Results There was significant difference in setup errors between group A and group B.The setup errors in the left-right direction (X),cranial-caudal direction (Y) and anterior-posterior direction (Z) were (0.19±0.14) cm,(0.17±0.12) cm and (0.13±0.11) cm in group A,respectively.On the contrary,the setup errors in X,Y and Z were (0.24±0.19) cm,(0.25±0.21) cm and (0.22±0.18) cm in group B,respectively.The rotational errors were 0.05°±0.02° in group A,comparing with 0.5°±0.21° in group B (P =0.00).The PTV expanded margin in group A was 0.56 cm in X direction,0.51 cm in Y direction,0.40 cm in Z direction,in comparing with 0.73 cm,0.78 cm and 0.67 cm in group B,respectively.Group A remarkably reduced the PTV,pelvis,small intestine,bladder and rectum irradiated volumes [(1 167±271) mm^3 vs (1 379±297) mm^3,(84±12) mm^3 vs (130±17) mm^3,(81±51) mm^3 vs (117±64)mm^3,(62±40) mm^3 vs (75±47) mm^3,(21±16) mm^3 vs (31±21) mm^3].Conclusion Popliteal fossa fixed method can reduce setup errors and improve the stability of positioning,more suitable in precise radiotherapy for postoperative cervical cancer patients,which has the value of further validation.

关 键 词:图像引导放疗 子宫颈肿瘤 体位固定 摆位误差 

分 类 号:R737.33[医药卫生—肿瘤] R730.55[医药卫生—临床医学]

 

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