锥形束CT评价直立体位下上气道正常值:山东地区6-19岁人群测量分析  

The normal measurements of the upper airway in people from Shandong aged 6-19 years old using cone-beam CT

作　　者：王松[1] 蒋英英[1,2] 郝建忠[2] 

机构地区：[1]潍坊医学院口腔医学院,山东省潍坊市261053 [2]潍坊医学院附属医院口腔科,山东省潍坊市261031

出　　处：《中国组织工程研究》2015年第7期1143-1148,共6页Chinese Journal of Tissue Engineering Research

基　　金：潍坊医学院附属医院科技创新基金青年项目(K12QC1008)~~

摘　　要：背景:随着锥形束CT在口腔颅颌面部的应用越来越广泛,明确正常人群的上气道指标对于诊断和预防气道相关的异常有重要意义。目的:确定山东地区6-19岁人群上气道的长度、宽度、横截面积及体积的锥形束CT测量值范围,为山东儿童及青少年上气道阻塞的诊断及治疗提供参考指标。方法:对254例(男120例,女134例)山东地区健康的6-19岁人群的锥形束CT图像进行分析,应用Mimics10.01软件分别测量鼻咽、腭咽、舌咽3个平面的矢状径、横径、横截面积及各部分的体积,确定正常值范围,还利用独立样本t检验分析性别差异,并计算95%置信区间。结果与结论:得出山东地区正常6-19岁人群上气道各径线、横截面积及体积的正常值范围及男女间差异对比,得出8-9岁、10-11岁、16-17岁、18-19岁上气道的部分指标存在性别差异。提示上气道的径线、横截面积及体积的正常值及95%置信区间为本地区青少年儿童上气道阻塞的诊断及评估治疗后上气道恢复解剖形态情况提供参考依据。BACKGROUND：With the extensive application of cone-beam CT in oral and craniofacial surgery, a clear airway indicator for normal population has important implications for the diagnosis and prevention of airway-related abnormalities. OBJECTIVE：To determine the cone-beam CT measurements of the upper airway （length, width, cross sectional area and volume） in populations aged 6-19 years from Shandong, so as to provide a reference marker for the diagnosis and treatment of upper airway obstruction in local children and adolescents. METHODS：Total y 254 healthy children （120 males and 134 females） aged 6-19 years from Shandong were subject to cone-beam CT scan of the upper airway. Mimics10.01 was used to measure the sagittal diameter, transverse diameter, cross-sectional area and volume of nasopharynx, palatopharynx, glossopharyngeal planes, and then the normal value range was confirmed. Independent-sample t-test was used for analysis of gender difference and 95%confidence interval was calculated. RESULTS AND CONCLUSION：There were gender differences in a part of indicators of the upper airway among 8-9 years, 10-11 years, 16-17 years, 18-19 years groups. These findings indicate that the normal values of radial lines, cross sectional area and volume of the upper airway as wel as 95%confidence interval value provide references for the diagnosis of upper airway obstruction and post-treatment evaluation of anatomic form of the upper airway in local children and adolescents.

关 键 词：组织构建 组织工程 上气道 儿童 青少年 正常值 锥形束CT 山东 

分 类 号：R318[医药卫生—生物医学工程]