中药注射液联合生长抑素对轻、中度急性胰腺炎血淀粉酶的干预作用及疗效评估  

Danshen injection combined with somatostatin for treatment of mild or moderate acute pancreatitis: Curative effect and impact on serum amylase levels

作　　者：刘路培[1] 

机构地区：[1]柳州市人民医院急诊科,广西壮族自治区柳州市545006

出　　处：《世界华人消化杂志》2015年第8期1350-1353,共4页World Chinese Journal of Digestology

摘　　要：目的:探讨临床对急性胰腺炎(acute pancreatitis,AP)患者实施中药注射液配合生长抑素治疗的疗效及其对血淀粉酶的影响.方法:选取2013-05/2014-05来柳州市人民医院治疗的AP患者共68例,随机将其等分成2组,对照组给予单纯生长抑素用药,观察组增加丹参注射液治疗,评估2组治疗后的疗效与血淀粉酶改善情况.结果:治疗后,观察组可取得91.2%的临床总疗效,要显著性高于对照组的76.5%(P<0.05).治疗前,2组的血淀粉酶水平对比相仿(P>0.05),经治疗后均出现改善,且观察组相比对照组下降更明显(P<0.05).2组治疗期间均有不良症状发生,观察组是5.9%与对照组的20.6%相比更低(P<0.05).结论:对AP患者实施丹参注射液配合生长抑素进行治疗,疗效更显著,安全性更佳,可有效降低血淀粉酶水平.AIM： To investigate the curative effect of Danshen injection combined with somatostatin in the treatment of mild or moderate acute pancreatitis（AP）, and the impact on serum amylase levels. METHODS： From May 2013 to May 2014, 68 mild or moderate AP patients treated at ourhospital were randomly divided into two groups： a control group and a study group. The control group was given somatostatin alone, while the study group was given Danshen injection on the basis of somatostatin. The curative effect and the improvement of serum amylase levels were compared for the two groups. RESULTS： After treatment, the total curative effect was significantly higher in the study group than in the control group（P〈0.05）. Before treatment, the levels of serum amylase between the two groups were similar. After treatment, serum levels of amylase declined in both groups, and the decline was more significant in the study group（P〈0.05）. Both groups had adverse symptoms during the treatment. The rate of adverse symptoms was significantly lower in the study group than in the control group（5.9% vs 20.6%, P〈0.05）. CONCLUSION： Danshen injection combined with somatostatin is effective and safe in the treatment of AP, and the combination therapy can also reduce serum amylase levels effectively.

关 键 词：丹参注射液 生长抑素 急性胰腺炎 血淀粉酶 

分 类 号：R576[医药卫生—消化系统]