胃肠间质瘤危险度评估方法的再认识  

Re-appraisal of risk assessment schemes in gastrointestinal stromal tumors

作　　者：汪明[1] 曹晖[1] 

机构地区：[1]上海交通大学医学院附属仁济医院胃肠外科,200127

出　　处：《中华胃肠外科杂志》2015年第4期309-312,共4页Chinese Journal of Gastrointestinal Surgery

基　　金：国家自然科学基金（81272743）;上海市科学技术委员会项目（13XDl402500,13411950902）

摘　　要：胃肠间质瘤（GIST）生物学行为多样，准确判断肿瘤的复发风险是一个至关重要的临床问题。 GIST复发危险度的评估体系已经经历了数次变革，但仍有改进和提升的空间。各种病理形态学指标、基因突变特征及其他分子标记物有望在不久的将来丰富到 GIST 危险度评估体系中去，在肿瘤个体化治疗的新形势下，GIST危险度的评估必将越来越多元化。The biological behavior of gastrointestinal stromal tumor （GIST） is highly variable. To assess the risk of recurrence of the primary tumor accurately is a key challenge. The risk assessment system of GIST has experienced several revolutions. The present accepted risk stratification scheme is still to be consummated. The pathological morphological characteristics, mutational features, and other biomarkers are helpful to improve the risk assessment system. The risk assessment of GIST in the future will be more and more diversified.

关 键 词：胃肠间质瘤 危险度评估 风险分级 预后 

分 类 号：R735[医药卫生—肿瘤]