昆明市1661例不育男性精液质量分析  

Investigation on the sperm quality of 1661 males in Kunming

作　　者：陈欣欣[1] 寸金涛 李霖华[1] 

机构地区：[1]昆明市妇幼保健院遗传室,云南昆明650031

出　　处：《云南医药》2015年第1期25-27,共3页Medicine and Pharmacy of Yunnan

摘　　要：目的分析昆明市不育男性精液情况,了解昆明市不育男性精液质量现状。方法采用计算机辅助精子分析系统(computer-aided sperm analysis,CASA),按照《世界卫生组织人类精液检查与处理实验室手册》,使用清华同方CASAAQH-Ⅲ仪器,对2012年1月—2013年12月到我院不孕症门诊就诊的1661例不育男性精液进行质量分析。结果 1661例不育男性精液量(3.16±1.68)m L,p H值(7.31±0.20),精子浓度(36.96±23.11)×106/m L,精子总数(108.47±104.61)×106/次,前向运动精子(29.15±16.95)%。精液正常557例(33.53%),精液异常1104例(66.47%),依次为前向运动精子比例异常占56.11%、精子总数异常占24.26%、精子浓度异常占21.43%、p H值异常占19.99%、液化异常占17.82%、精液量异常占9.81%。男性不育患者中精子浓度正常者占78.57%,无精子症占5.54%,少精子症占15.89%,弱精子症占53.54%。结论我市不育男性精液质量明显下降,表现为66.47%的不育男性患者存在精液质量异常,精子活力异常所占比例最高,提示精液质量下降是导致男性不育的主要因素。Objective To investigate the sperm quality of male infertility in Kunming area. Methods According to 《HO laboratory manual for the examination and processing of human semen 》, all the 1661 semen samples of the male infertility were analyzed through CASA（CASAA-QH- Ⅱ , made by Tsinghua Tongfang ）, and all the patients who hospitalized in our fertility clinics were because of infertility from Jan. 2012 to Dec. 2013. Results Among the 1661 males infertility ,the semen volume was （ 3.16 ± 1.68 ） mL, pH value was （ 7.31 ± 0.20 ） , the sperm concentration was （ 36.96 ± 23.11 ） × 106/mL, the total sperm number was （ 108.47 ± 104.61 ） × 106 spermatozoa per ejaculate, the progressive sperm motility was （ 29.15 ± 16.95 ） % o The sample with normal sperm quality accounted for 33.53%（557/1661 ） in contrast with abnormal 66.47 % （1104/1661 ） .Among the abnormal samples, there were 932（56.11%） with abnormal progressive sperm motility, 403 （24.26%） with abnormal total sperm number, 356 （ 21.43% ） with abnormal concentration , 332 （ 19.99% ） with abnormal pH value, 296 （ 17.82% ） with abnormal liquefying time,163 （ 9.81% ） with abnormal semen volume. 78.57 % of infertile males had the normal sperm concentration , 5.54 % of azoospermia, 15.89 % of oligozoospermia, and 53.54 % of asthenospermia .Conclusion the semen quality of the male infertility population in Kunming area has a marked decreased, 66.47 % males infertility has an abnormal sperm quality and mostly for abnormal sperm motility. All that show us the drop in the semen quality is a main factor for male infertility.

关 键 词：男性不育 计算机辅助精子分析系统 精液分析 

分 类 号：R698.2[医药卫生—泌尿科学]