乳腺癌超声弹性成像面积比与其组织学分级、临床分期关系的初步研究  

Relationship among breast cancer area ratio of ultrasound elastography,its histological grade and clinical stage

作　　者：乔向彬[1] 肖保军[1] 蔡雪莲[1] 郭海红[1] 吴秀平[2] 杜毅力[2] 

机构地区：[1]首都医科大学大兴医院超声科,北京市102600 [2]遵义医学院附属医院超声科

出　　处：《临床超声医学杂志》2015年第3期166-168,共3页Journal of Clinical Ultrasound in Medicine

摘　　要：目的探讨乳腺超声弹性成像面积比（AR）对乳腺癌患者病情发展及预后评估的参考价值。方法回顾性分析105例经病理结果证实的乳腺癌患者临床资料,术前行乳腺常规超声及超声弹性成像检查,分析乳腺癌患者不同组织学分级间、不同临床分期间AR参数的变化情况。结果术前以AR≥1.5为诊断恶性的标准,73例恶性,诊断符合率为69.52%。超声弹性成像AR在各组织学分级、临床分期组间差异有统计学意义（P〈0.05）：组织学分级Ⅰ～Ⅲ级的AR值分别为1.210±0.018、1.470±0.126、1.600±0.028,临床分期Ⅰ～Ⅳ期AR值分别为1.230±0.056、1.540±0.017、1.580±0.025及1.620±0.023,即AR在组织分级较高及临床分期较晚时增大。结论 AR可为乳腺癌病情发展及预后评估提供有价值的参考信息。Objective To investigate the value of breast cancer area ratio （AR） of ultrasound elastography in assessing breast cancer progression and prognosis. Methods A retrospective analysis of 105 cases of breast cancer carrying out conventional ultrasound and ultrasound elastography examination before operation, and finally confirmed by postoperative pathological findings.The difference of AR among breast cancer patients with different histological grade and different clinical stage was analyzed. Results AR ～ 1.5 for the diagnosis of malignant lesions, there were 73 patients,the coincidence rate was 69.52%. There was significant difference of ultrasound elastography AR in different histological grade and clinical stage group （P〈0.05）. The AR value of the histological grading I ～ Ⅲ were 1.210±0.018,1.470±0.126,1.600±0.028,respectively. The AR value of clinical stage I ～Ⅳ were 1.230±0.056,1.540±0.017,1.580±0.025,1.620±0.023,respectively. The results showed that AR ratio was increased in high histological grade and in advanced clinical stage. Conclusion It can be inferred that AR may become one of the indicators to assessing progression and prognosis of breast cancer.

关 键 词：超声检查 弹性成像 面积比 临床分期 

分 类 号：R737.9[医药卫生—肿瘤] R445.1[医药卫生—临床医学]