机构地区:[1]哈尔滨医科大学附属第一医院眼科视光学中心,150001
出 处:《眼科》2015年第2期112-116,共5页Ophthalmology in China
摘 要:目的观察配戴角膜塑形镜后角膜表面曲率、前房深度和前房体积的变化,并探讨角膜生物力学与角膜表面变化的相关性。设计回顾性病例系列。研究对象哈尔滨医科大学附属第一医院眼科医院视光学中心在2013年1-4月间验配角膜塑形镜的患者24例(24眼),年龄8~16岁,等效球镜度-4.0^-5.0 D。方法应用Pentacam眼前节分析系统分别在戴镜前、戴镜1夜和1个月时测量中央角膜厚度(CCT)、角膜前表面平坦K值(Kf)、陡峭K值(Ks),角膜后表面Kf、Ks以及前房深度(ACD)和前房体积(ACV)。眼反应分析仪(ORA)测量角膜滞后量(CH)和角膜阻力因子(CRF)。主要指标等效球镜度(SE),角膜前表面Kf、Ks值,角膜后表面Kf、Ks值,ACD和ACV。结果配戴角膜塑形镜1夜后SE降低(-2.35±0.85)D。角膜前表面变平坦,前表面Kf、Ks值分别减少(1.31±0.64)D、(1.20±0.76)D。戴镜1个月后SE较戴镜前降低(-4.02±0.54)D,前表面Kf、Ks值分别减少(2.54±1.13)D、(2.90±1.01)D。戴镜1夜后,ACD、ACV分别降低(0.02±0.02)mm、(1.71±3.54)mm3,戴镜1个月后分别下降(0.03±0.02)mm、(4.96±2.25)mm3。戴镜1个月时,ACD、ACV与戴镜前和戴镜1天时比较差异有统计学意义(t=23.081,P=0.000;t=8.847,P=0.000;t=8.877,P=0.000;t=10.772,P=0.000)。角膜后表面Kf、Ks值在戴镜1个月后与戴镜前比较均无明显变化(t=-0.365,P=0.718;t=-0.238,P=0.814)。CH、CRF与ACD、ACV的变化无明显相关性(P均>0.05),但随着CH、CRF增加,ACD、ACV的变化有减少的趋势。结论角膜塑形镜能有效地矫正近视,戴镜后角膜被整体压平,压平的程度可能受角膜生物力学属性的影响。Objective To observe the changes of corneal curvature, anterior chamber depth (ACD) and anterior chamber volume (ACV) after wearing orthokeratology lens and investigate the relationship between corneal biomechanical properties and changes of corneal surfaces. Design Retrospective cases series. Participants Twenty-four orthokeratology patients (24 eyes) from Janurary to April in 2013 at the Optometry Center of the Ophthalmology Department in the First Affiliated Hospital of Harbin Medical University with age ranged from 8-16 years old, and spherical equivalent (SE) varied from -4.00~-5.00 D. Methods We applied Pentacam to analyze central corneal thickness (CCT), anterior flat keratometry (anterior Kf), anterior steep keratometry (anterior Ks), posterior fiat keratometry (posterior Kf), posterior steep keratometry (posterior Ks), ACD, ACV before, overnight and after one month wearing or- thokeratology lens. Ocular response analyzer (ORA) was used to analyze corneal hysteresis (CH), corneal resistance factor (CRF) be- fore and after wearing orthokeratology. Main Outcome Measures Mean SE, anterior Kf, anterior Ks, posterior Kf, posterior Ks, ACD and ACV. Results After overnight wearing orthokeratology lens, the SE value significantly dropped (-2.35±0.85) D, anterior corneal surface became flattened, the value of anterior Kf reduced (1.31±0.64) D and anterior Ks decreased (1.20±0.76) D. After one-month wearing orthokeratology lens, SE decreased (-4.02 ±0.54) D, the value of anterior Kf and Ks decreased (2.54 ± 1.13) D and (2.90 ± 1.01) D respectively. ACD and ACV respectively reduced (0.02±0.02) mm and (1.71±3.54) mm^3 after overnight wearing and with one- month wearing respectively reduced (0.03±0.02)mm and (4.96±2.25)mm^3. ACD and ACV significantly decreased after one-month, compared to the values before and overnight wearing orthokeratology (t=23.081, P=0.000; t=8.847, P=0.000; t=-8.877, P=-0.000; t=10.772, P=0.000
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