建立膀胱癌丝裂霉素热灌注化疗不良反应的监测护理模式  

作　　者：钟肖红[1] 杨建安[1] 王斌[1] 唐鸿生[1] 郭龙斌[1] 

机构地区：[1]广州医科大学附属肿瘤医院手术室,510095

出　　处：《国际医药卫生导报》2015年第7期892-894,共3页International Medicine and Health Guidance News

基　　金：广东省医学科学技术研究基金（A2013293）

摘　　要：目的探讨丝裂霉素热灌注化疗治疗膀胱癌的不良反应并建立其监测与护理模式。方法收集125例术后丝裂霉素热灌注化疗的膀胱癌病例，监测化疗期间的不良反应，制定其分类、等级、预警值，开发不良反应的监测程序并建立相应的护理制度。结果不良反应主要有膀胱疼痛（32．0％）、尿频尿急感（20．8％）、恶心呕吐（15．2％）、腹泻腹痛（8．0％）等。根据不良反应的分布，建立监测表，设定不良反应的等级（1—3级）、预警值和相应的护理干预程序。结论建立膀胱癌丝裂霉紊热灌注化疗不良反应的护理监测模式，使不良反应的监测和护理具有较好的操作性和实效性。Objective To explore the adverse reactions of thermal perfusion of mitomycin C for bladder carcinoma and to establish the monitoring and nurse model.Methods 125 patients with bladder carcinoma undergoing thermal perfusion of mitomycin C after the removal of tumors were collected and retrospectively analyzed.The adverse reactions were monitored.The values of classification,grade,and warning were set.The monitoring procedures and corresponding nurse system of adverse reactions Were established.Results The main adverse reactions included bladder pain (32.0％,40/125),frequent urination or feeling a sense of urgency (20.8％,26/125),nausea or vomiting (15.2％,19/125),diarrhea or abdominal pain (8.0％,10/125),etc.Adverse reactions monitoring table was set according its frequency;they were classified and graded(1-3 grades).Warning value and nurse procedures were set.Conclusions The establishment of the monitoring procedures and corresponding nurse system of adverse reactions is practical and effective for thermal perfusion of mitomycin C for bladder carcinoma.

关 键 词：膀胱癌 热灌注化疗 不良反应 护理 监测 

分 类 号：R735[医药卫生—肿瘤]