腹腔镜技术对结直肠癌淋巴结微转移的影响  

Effect of Laparoscopic Technique on Lymph Node Micrometastasis in Patients with Colorectal Cancer

作　　者：郭朝阳[1] 秦章禄[1] 袁庆文[2] 何德[1] 

机构地区：[1]萍乡市人民医院胃肠外科,江西萍乡337000 [2]南昌大学第二附属医院普外科,南昌330006

出　　处：《实用临床医学（江西）》2015年第3期36-37,69,共3页Practical Clinical Medicine

摘　　要：目的探讨腹腔镜技术对结直肠癌淋巴结微转移的影响。方法将40例结直肠癌患者分为腔镜组与开腹组,采用免疫组织化学染色法检测阴性淋巴结中CEA、CK20的表达情况,比较分析2组表达差异性。结果腹腔镜组常规病理阴性淋巴结115枚,其中CEA阳性17枚(14.8%),CK20阳性10枚(11.5%);开腹组109枚,其中CEA阳性14枚(12.8%),CK20阳性13枚(11.9%),2组比较差异无统计学意义(P>0.05)。结论结直肠癌腹腔镜手术与开腹手术比较并不增加癌细胞区域淋巴结的微转移。ABSTRACT:Objective To investigate the effect of laparoscopic technique on lymph node micro-metastasis in patients with colorectal cancer.Methods A total of 40 patients with colorectal canc-er were randomly assigned into laparotomy group and laparoscopic surgery group.The expression of CEA and CK20 in negative lymph nodes was detected using immunohistochemical staining,and was compared between the both groups.Results There were 115 negative lymph nodes in laparo-scopic surgery group.Among them,positive CEA expression was found in 17 (14.8%)and posi-tive CK20 expression in 10 (11.5%).There were 109 negative lymph nodes in laparotomy group. Among them,positive CEA expression was found in 14 (12.8%)and positive CK20 expression in 13 (11.9%).No significant differences in the expression of CEA and CK20 were found between the two groups (P >0.05).Conclusion Laparoscopic colorectal cancer surgery does not increase the lymph node micrometastasis compared with laparotomy.

关 键 词：腹腔镜 结直肠癌 微转移 免疫组化 

分 类 号：R735.37[医药卫生—肿瘤]