突发性聋合并高血压病患者的纯音测听特征与疗效分析  

The study of the pure tone audiometry characteristics and curative effect in sudden hearing loss patients with hypertension

作　　者：李倩[1] 王大勇[1] 王洪阳[1] 兰兰[1] 韩冰[1] 齐悦[1] 关静[1] 尹自芳[1] 吴子明[1] 王秋菊[1] 

机构地区：[1]中国人民解放军总医院耳鼻咽喉头颈外科解放军耳鼻咽喉研究所,北京100853

出　　处：《临床耳鼻咽喉头颈外科杂志》2015年第8期748-752,共5页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：国家重大科学研究计划项目(No:2014CB943001);国家自然基金重点项目(No:30830104);国家自然基金重大国际合作项目(No:81120108009);全军"十二五"重点项目(No:BWS11J026);解放军总医院博士创新基金项目(No:12BCZ05)联合资助

摘　　要：目的：探讨突发性聋合并高血压病患者的纯音测听特征,并分析对比不同临床特征患者间的疗效。方法：回顾性分析157例（168耳）突发性聋合并高血压病患者的纯音测听结果,比较不同性别、年龄、患侧、高血压病程、有无诱因、伴发症状、合并其他疾病患者间纯音听阈及各频率的差异。结果：合并高血压病患者在同期突发性聋患者（874例）中的患病率为17.96%。其中男性合并高血压病的患病率为28.69%（103/359）,女性为19.42%（54/278）,男女间差异有统计学意义（P〈0.01）。突发性聋患者34-44岁合并高血压病的患病率为12.69%（25/197）,45-59岁为22.51%（70/311）,60-69岁为47.62%（40/84）,≥70岁为48.89%（22/45）,各年龄间患病率差异有统计学意义（P〈0.01）。突发性聋合并高血压病患者听力曲线为低频下降型18耳（10.71%）,高频下降型61耳（36.31%）,平坦型41耳（24.40%）,全聋型48耳（28.57%）。纯音听阈受损低频、中频、高频依次加重,三者间差异有统计学意义（P〈0.01）。患者纯音测听各频率听阈均值在不同性别、不同年龄、心血管危险分层患者间的差异无统计学意义（P〉0.05）。纯音测听各频率听阈单侧聋患者明显高于双侧（P〈0.05）。125Hz、250Hz、500Hz、1kHz听阈均值在不同高血压病程患者间存在统计学差异（P〈0.05）。突发性聋合并高血压病治疗总有效率（19.64%）明显低于突发性聋无高血压病患者（61.57%）,P〈0.01。高血压病程0-1年与病程〉10年的患者间、不同心血管危险分层患者间的差异有统计学意义（均P〈0.05）。结论：突发性聋合并高血压的患病率男性高于女性。患病率随突发性聋患者的年龄增加与合并疾病而升高。听阈受损程度高频、中频高于低频。突发性聋合并高血压病患者的治疗有效率较低,且高血压病程越长、心血管危险分层越高治疗有效率越�Objective：To investigate the pure tone audiometry characteristics and curative effect in sudden hearing loss patients with hypertension.Method：One hundred and fifty-seven inpatients（168ears）with hypertension suffered from sudden hearing loss were included in this study.We retrospectively analyzed the audiological index of these patients by comparing the pure tone audiometry（PTA）among patients in the aspects of gender,age,affected side,duration of hypertension,with or without inducement,concomitant symptoms and other combined diseases.The hearing threshold at different frequency was also compared,as well as the curative effect among patients with diverse audiological characteristics.Result：Of the contemporaneous sudden hearing loss patients（874cases）,the prevalence of hypertension was17.96%,where the male ones accounted for.28.69%（103/359）and the female ones accounted for 19.42%（54/278）respectively with statistically significant difference between genders（P〈0.01）.The prevalence of hypertension in 34-44 years old group,45-49 years old group,60-69 years old group and over 70 years old group was 12.69%（25/197）,22.51%（70/311）,47.62%（40/84）,48.89%（22/45）respectively,which were statistically different（P〈0.01）.The number of impaired ears with audiogram configuration characterized by rise type,downslope type,flat type and completely deafness type was 18（10.71%）,61（36.31%）,41（24.40%）,and 48（28.57%）,respectively.The decrease of hearing threshold in PTA were increasingly severe as the increasing impaired-frequency,and the difference of the degree of hearing impairment among these three types of frequencies was statistically significant（P〈0.01）.The hearing threshold means of each frequency had no significant difference among patients with various gender,age and Cardiovascular Risk Stratification（P〉0.05）.The hearing threshold means of each frequency of unilateral hearing loss patients was significantly higher than that of bilateral hearing loss p

关 键 词：听觉丧失 突发性 高血压 测听法 纯音 治疗结果 

分 类 号：R764.43[医药卫生—耳鼻咽喉科]