2型糖尿病合并消化性溃疡的临床特征  

Clinical characteristic of peptic ulcer associated with type 2 diabetes

作　　者：刘仲栋[1] 李丽艳[1] 

机构地区：[1]天津市南开区中医医院内分泌科,天津市300102

出　　处：《世界华人消化杂志》2015年第10期1690-1694,共5页World Chinese Journal of Digestology

摘　　要：目的:探讨2型糖尿病合并消化性溃疡患者的临床特征.方法:比较天津市南开区中医医院收治的116例2型糖尿病合并消化性溃疡患者(实验组)和110例非糖尿病消化性溃疡患者(对照组)的临床资料,分析两组患者消化性溃疡发生部位、最大直径、治疗效果、幽门螺杆菌(Helicobacter pylori,H.pylori)根除率以及并发症发生情况上的差异性.结果:实验组患者胃溃疡发生率显著高于对照组(50.00%vs 36.36%),十二指肠溃疡发生率显著低于对照组(31.03%vs 50.91%),差异具有统计学意义(P<0.05);实验组患者消化性溃疡最大直径>10.0 mm者所占比例显著高于对照组(31.90%vs 25.45%),差异具有统计学意义(P<0.05);实验组患者愈合率和H.pylori根除率均显著低于对照组(28.45%vs40.91%、45.33%vs 71.43%),差异具有统计学意义(P<0.05);实验组患者贫血发生率显著高于对照组(76.72%vs 59.09%),差异具有统计学意义(P<0.05).结论:2型糖尿病患者消化性溃疡发病部位主要为胃部,病灶直径较大较深,出血风险更高,临床治疗难度更大,愈合和H.pylori根除效果较单纯消化性溃疡者差.AIM：To explore the clinical characteristics of peptic ulcer associated with type 2 diabetes.METHODS：One hundred and sixteen patients with type 2 diabetes and peptic ulcer were included in an experiment group,and 110 peptic ulcer patients without diabetes were included in a control group.The location of ulcer,maximum diameter,therapeutic effects,the rate of Helicobacter pylori（H.pylori）eradication,and complication were compared for the two groups.RESULTS：The rate of gastric ulcer for the experiment group was significantly higher than that for the control group（50.00%vs 36.36%,P〈 0.05）,while the rate of duodenal ulcer for the experiment group was significantly lower than that for the control group（31.03%vs 50.91%,P 〈0.05）.The rate of maximum ulcer diameter〉10.0 mm for the experiment group was significantly higher than that for the control group（31.90%vs 25.45%,P〈 0.05）,while the rates of healing and H.pylori eradication for the experiment group were significantly lower than those for the control group（28.45%vs 40.91%,45.33%vs 71.43%,P 〈0.05）.The rate of anemia for the experiment group was significantly higher than that for the control group（76.72%vs 59.09%,P 〈0.05）.CONCLUSION：Peptic ulcer in patients with type 2 diabetes tends to affect the stomach and have larger lesions,a high rate of bleeding,and low rates of healing and H.pylori eradication.

关 键 词：2型糖尿病 消化性溃疡 特点 

分 类 号：R573.1[医药卫生—消化系统] R587.1[医药卫生—内科学]