硝苯地平诱导药物性牙龈肥大牙周基础治疗临床效果评价  

The clinical effect of initial periodontal therapy on gingival enlargement induced by nifedipine

作　　者：刘海杰[1] 潘亚萍[1] 

机构地区：[1]中国医科大学附属口腔医院牙周科,辽宁省口腔医学研究所,沈阳110002

出　　处：《中国实用口腔科杂志》2015年第2期86-88,92,共4页Chinese Journal of Practical Stomatology

基　　金：国家自然科学基金(81271153)

摘　　要：目的评价牙周基础治疗对硝苯地平诱导药物性牙龈肥大的治疗效果。方法选择2012年6月至2013年6月于中国医科大学附属第四医院心内科门诊与病房、中国医科大学口腔医院牙周科门诊患者中诊断为高血压且服用硝苯地平后出现牙龈增生者23例,在初诊及牙周基础治疗后1、3、6个月分别记录患者牙周指标(牙龈增生指数、菌斑指数、出血指数和探诊深度等),分析牙龈增生指数与菌斑指数的相关性。结果所有患者各牙周指标在牙周基础治疗后1、3、6个月均有明显改善,与初诊比较差异有统计学意义(P<0.05);牙龈增生指数与菌斑指数存在显著正相关(P<0.05)。结论牙周基础治疗有利于硝苯地平诱导的药物性牙龈肥大的临床治疗。Objective To evaluate the clinical effect of initial periodontal therapy on gingival enlargement induced by nifedipine. Methods Totally 23 patients with gingival enlargement induced by Nifedipine were included in this study. The plaque index （PLI）, bleeding index （BI）, probing depth （PD） and gingival overgrowth index （GOI） were scored at the first visit; all the patients accepted initial periodontal therapy after the examination. The above indices were examined again at 1 month, 3 months and 6 months after initial periodontal therapy.And the correlation between GOI and PLI was analyzed. Results PLI, BI, PD and GOI had significant difference between different time points and the first visit （P 〈 0.05）, and there was a significantly positive correlation between GOI and PLI. Conclusion Initial periodontal therapy is effective in reducing drug-induced gingival enlargement.

关 键 词：药物性牙龈肥大 硝苯地平 牙周基础治疗 

分 类 号：R78[医药卫生—口腔医学]