羟磷灰石颗粒体外堆压间隙显微CT研究  

Evaluation of space between hydroxyapatite particle in vitro by Micro-CT

作　　者：陈筑苏[1,2] 吴王喜[1,3] 周磊[1,3] 

机构地区：[1]南方医科大学附属口腔医院 [2]广东省口腔医院牙体牙髓科,广州510280 [3]广东省口腔医院种植中心,广州510280

出　　处：《中国实用口腔科杂志》2015年第2期112-114,共3页Chinese Journal of Practical Stomatology

基　　金：广东省卫生厅广东省医学科学技术研究基金项目(A2013095)

摘　　要：目的通过显微CT体外评价,比较3种不同直径羟磷灰石颗粒外部间隙分布情况,探讨材料外部间隙对临床运用的影响。方法 2014年3—4月于广州科学城显微CT实验室对颗粒直径分别为0.25-1 mm、0.4-1 mm、1-2 mm的3种人工骨材料进行体外固定,采用显微CT扫描,评价各自的间隙排列。结果 1-2 mm组羟基磷灰石颗粒压实堆积后显微CT下显示材料颗粒排列松散,颗粒团块间存在较大空隙,间隙率为61.75%;0.25-1 mm和0.4-1 mm组材料颗粒排列较为均匀,颗粒团块间存在间隙较小,间隙率分别为27.33%和42.44%。结论显微CT可用于颗粒移植材料的微观物理参数评估,0.25-1 mm组羟磷灰石颗粒压实后颗粒团块内部排列紧密,临床上有利于植骨后稳定成骨空间。ObjectiveTo evaluate the distribution of the space between hydroxyapitite particle from 3 types of sizes by Micro-CT and the clinical effect.MethodsFrom March to April 2014,Micro-CT laboratory,Guangzhou Scientific City,Micro-CT scanning was performed for 3 different diameters of hydroxyapitite particle,0.25 - 1 mm,0.4 - 1 mm,1-2 mm respectively by packed in vitro.ResultsGroup 1 - 2 mm particle showed loose and irrregular distribution,the space rate 61.75%;groups 0.25 - 1 mm and 0.4 -1 mm showed uniform and compact distribution,the space rate27.33% and 42.44%.ConclusionMicro-CT is a practical method for studying graft material partical;group 0.25 - 1mm is fit for clinic for its uniform and compact distribution.

关 键 词：显微CT 骨移植 颗粒 间隙 羟磷灰石 

分 类 号：R78[医药卫生—口腔医学]