脂蛋白(a)与脑卒中关系的临床观察  

THE RELATIONSHIP BETWEEN LIPOPROTEIN(a) AND STROKE

作　　者：刘惠苗[1] 仇福成[1] 韩瑞[1] 解冰川[1] 张振清[1] 顾平[1] 

机构地区：[1]河北医科大学第一医院神经内科,河北省石家庄市050031

出　　处：《中国煤炭工业医学杂志》2015年第3期373-375,共3页Chinese Journal of Coal Industry Medicine

基　　金：河北省卫生厅科研课题(编号:20130580)

摘　　要：目的探讨脂蛋白(a)水平与脑卒中的关系。方法采用ELISA双抗体夹心法检测100例脑梗死患者、78例短暂性脑缺血发作患者、66例脑出血患者及100例健康查体者血清脂蛋白(a)水平及其异常率。结果脑梗死组及短暂性脑缺血发作患者脂蛋白(a)水平和异常率较脑出血组及健康对照者均增高,差异具有统计学意义(P<0.05),脑出血组患者脂蛋白(a)水平和异常率较健康对照组差异无统计学意义(P>0.05)。结论高血清脂蛋白(a)与缺血性脑卒中的发生有关。Objective To investigate the relationship between lipoprotein （a） levels and stroke. Methods The double antibody ELISA was used to detect serum lipoprotein （a） level and abnormal rate of 100 cases of patients with cerebral infarction, 78 patients with transient ischemic attack, 66 cases of intracerebral hemorrhage patients and 100 healthy physical. Results The lipoprotein（a） level and its abnormal rate in the cerebral infarction group and transient ischemic attack group were higer than the intracerebral hemorrhage group and healtry controls, the difference was statistically significant （P〈0.05）. But they were no significant difference between the intracerebral hemorrhage group and healthy controls （P〉0.05）. Conclusion Hige serum lipoprotein（a） is associated with ischemic stroke.

关 键 词：脂蛋白(a) 脑卒中 缺血性 

分 类 号：R743.3[医药卫生—神经病学与精神病学]