真菌性角膜溃疡的临床病理探析  

The clinical and pathological analysis of fungal corneal ulcer

作　　者：陈智敏 曾敏智[2] 陈振谦[2] 

机构地区：[1]深圳市福田区第二人民医院眼科,广东深圳518049 [2]广州医科大学附属第二医院眼科,广东广州510260

出　　处：《黑龙江医药科学》2015年第2期89-90,共2页Heilongjiang Medicine and Pharmacy

摘　　要：目的：探讨真菌性角膜溃疡的临床病理学形态。方法：选取两院在2010-01~2014-01收治的真菌性角膜溃疡患者52例,对所有患者的角膜组织标本行HE染色和PAS染色,并对其病理学形态进行分析总结。结果：镰刀菌和曲霉菌是常见致病菌,且真菌性角膜溃疡的组织损害以广泛化脓性炎症为主,真菌可对角膜组织的直接破坏,并在角膜组织内产生大量的中性粒细胞的浸润。结论：对真菌性角膜溃疡进行病理学分析,可进一步明确真菌在角膜内的生长情况,对指导临床诊治具有重要意义。Objective： To investigate the clinical and pathological morphology of fungal corneal ulcer. Methods： 52 cases of fungal corneal ulcer in January,2010 to January,2014 were selected. Corneal tissue specimens of all patients were processed by HE staining and PAS staining,and finally with a pathological analysis. Results： Fusarium and Aspergillus are common pathogenic bacteria. Fungal corneal ulcer tissue damage was characterized by extensive purulent inflammation. Fungi can directly damage corneal tissue,and produce a large number of neutrophils within the corneal tissue. Conclusion： The pathological analysis of fungal corneal ulcer can further define the growth of fungi in cornea,and has important significance in clinicaldiagnosis and treatment.

关 键 词：真菌性角膜溃疡 病理 形态 

分 类 号：R772.2[医药卫生—眼科]