替吉奥单药治疗老年进行性胃癌的临床分析  

Clinical Analysis of S-1 in the Treatment of Gastric Cancer in Elderly Patients

作　　者：刘占京[1] 

机构地区：[1]河南中医学院第一附属医院药学部,郑州450000

出　　处：《中国医药导刊》2014年第6期1002-1003,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:对替吉奥单药治疗老年进行性胃癌患者的临床效果进行观察与分析。方法:将我院收治的28例老年进行性胃癌患者随机分为两组,一组为观察组,口服替吉奥胶囊,每天2次,每次40mg/m2。另一组为对照组,口服卡培他滨片,每天2次,每次1250mg/m2。在服药3个周期后,再对两组患者的临床疗效以及不良反应进行对比。结果:观察组患者的临床疗效率为78.6%,对照组患者的临床疗效率为71.4%,两组比较差异不明显,无统计学意义(P>0.05),但是观察组患者的不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。结论:替吉奥单药治疗老年进行性胃癌患者的临床效果显著。Objective：To study the clinical effects of S-1 in the treatment of elderly patients with gastric cancer.Methods：28 cases of elderly patients admitted to our hospital for advanced gastric cancer patients were randomly divided into two groups,one group for the observation group,S-1 capsule,2 times a day,each time 40mg/m2.Another group was control group,oral capecitabine tablets,2 times a day,each time 1250 mg/m2.In the medication after 3 cycles,and then to compare the clinical efficacy and adverse reactions of two groups of patients.Results：To observe the clinical therapeutic efficiency of the patient group was 78.6%,control group patients clinical treatment efficiency was 71.4%,difference between the two groups was not obvious,no statistical significance（P〉0.05）,but the adverse reactions observed group of patients was significantly lower than the control group,the difference was statistically significant（P〈0.05）.Conclusion：S-1 in the treatment of elderly patients with gastric cancer clinical effect is significant.

关 键 词：替吉奥胶囊 老年进行性胃癌 卡培他滨片 

分 类 号：R735.2[医药卫生—肿瘤]