神经生长因子治疗脑出血临床疗效观察  

Clinical Curative Effect of Nerve Growth Factor on Cerebral Hemorrhage

作　　者：赵建芹[1] 辛国强[2] 

机构地区：[1]济南军区总医院急诊科,济南250031 [2]济南军区总医院神经外科,济南250031

出　　处：《中国医药导刊》2014年第12期1469-1470,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:观察注射用鼠神经生长因子治疗脑出血的临床疗效。方法:选取脑出血患者78例,随机分为2组,对照组39例,应用胞二磷胆碱注射液0.5g,静滴,1次/d,观察组39例,应用注射用鼠神经生长因子18μg,肌内注射,1次/d,疗程4周,分别于治疗前及治疗后4周,对患者进行神经功能缺损评分及临床疗效评分。结果:治疗后,2组患者神经功能缺损评分较治疗前明显降低,差异有统计学意义(P<0.05)。治疗后4周,观察组神经功能缺损评分较对照组明显降低,临床有效率明显增高,差异均有统计学意义(P<0.05)。结论:注射用鼠神经生长因子可有效缓解脑出血患者的神经功能缺损。Objective： To observe the curative effect of nerve growth factor（NGF） on cerebral hemorrhage. Methods： 78 patients with cerebral hemorrhage were randomly divided into 2 groups, the control group（39 cases） were received intravenous drip of 0.5g Citicoline injection, once a day, for 4 weeks.The observation group（39 cases）were received intramuscular injection of 18μg mouse NGF, once a day, for 4 weeks.Before and after treatment, nerve dysfunction and clinical curative effect were scored for the two groups. Results：The nerve dysfunction score was lower in the two groups after treatment than before treatment（P〈0.05）.The nerve dysfunction was lower whereas the clinical curative effect was higher in the obseration group than in the control group after 4 weeks treatment（P〈0.05）.Conclusion： NGF can effectively alleviate the nerve dysfunction of patients with cerebral hemorrhage.

关 键 词：神经生长因子 脑出血 

分 类 号：R743.34[医药卫生—神经病学与精神病学]