放射性粒子治疗与基因治疗神经胶质瘤的概况  

General situation of radioactive particles therapy and gene therapy in gliomas

作　　者：徐延斌(综述)[1] 李建华(审校)[1] 

机构地区：[1]哈尔滨医科大学附属第四医院微创神经外科,哈尔滨150001

出　　处：《实用肿瘤学杂志》2015年第2期153-156,共4页Practical Oncology Journal

基　　金：黑龙江省科技攻关项目（GCl2C303-3）

摘　　要：神经胶质细胞瘤是恶性脑肿瘤中最常见的一种类型，约占中枢神经系统肿瘤的一半以上，且易复发。如何选择术后的治疗方案成为延长患者生存时间的关键。随着医学技术的发展，出现了放射性粒子近距离治疗和基因治疗等一些精确治疗手段。本文将对粒子治疗及基因治疗神经胶质瘤的现状分别阐述，结合其优劣势，探讨两者联合治疗的发展前景，以期更好地改善神经胶质瘤的预后。Glioma is the most common type among the malignant brain tumors ,and it accounts for almost half of central nervous system tumors .In addition,one of characters of glioma is easy to relapse .The key to pro-long the patients′survival time is how to choose appropriate treatments after surgical resection .With the develop-ment of medical technology ,precise approaches to treat these tumors are applied ,including radioactive particle im-plantation in brachytherapy and gene therapy .In this paper ,we discuss the status of the two therapies respective-ly,analyzing their superiority and inferiority ,and explore the prospects for the development of combined therapy in order to improve the prognosis of glioma better .

关 键 词：胶质瘤 粒子 近距离放射治疗 基因治疗 联合治疗 

分 类 号：R739.41[医药卫生—肿瘤]