脑梗死患者早期康复血清超敏C反应蛋白测定的临床意义  

Clinical Significance of Early Rehabilitation with Cerebral Infarction Patients in Serum High-sensitivity C-Reactive Protein

作　　者：李德欣[1] 肖占森[1] 李建华[2] 

机构地区：[1]北京市房山区第一医院检验科,北京102400 [2]北京市房山区第一医院神经内科,北京102400

出　　处：《中国医药导刊》2014年第7期1181-1182,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨血清超敏C反应蛋白(hs-CRP)水平对脑梗死(CI)患者检测的临床意义。方法:选择108例急性脑梗死(ACI)患者随机分为康复组及对照组。两组患者均给予神经内科常规治疗及护理。其中康复组接受早期康复训,两组患者于入院时及发病后30天分别进行Barthel指数、简化Fugl-Meyer运动功能评分和血清Hs-CRP含量测定。结果:康复组治疗前Barthel指数评分、简化Fugl-Meyer运动功能评定和hs-CRP水平与对照组比较无显著差异(P>0.05);治疗后康复组Barthel指数评分、简化Fugl-Meyer运动功能评定较对照组显著升高(P<0.000),而康复组血清hs-CRP水平显著低于对照组(P<0.000)。结论:血清hs-CRP与ACI关系密切,对诊断及治疗CI具有较高的临床应用价值,早期康复治疗可以降低急性CI患者血清hs-CRP水平。Objective： To explore serum high-sensitivity C-reactive protein（hs-CRP） concentration in patients with cerebral infarction（CI） of clinical signiifcance. Methods： Select the ifrst 108 cases of cerebral infarction（ACI） patients were randomly divided into rehabilitation group and control group. Two groups of patients were treated with conventional therapy and neurology care. Where rehabilitation group received early rehabilitation training, both groups of patients at the time of admission and 30 days after the onset of Barthel index were carried out to simplify the Fugl-Meyer motor function score and serum hs-CRP determination. Results：Rehabilitation group before treatment Barthel Index score, simplify no signiifcant difference （P〉0.05） Fugl-Meyer motor function assessment and hs-CRP levels in the control group;After treatment, rehabilitation group Barthel Index score, simpliifed Fugl-Meyer motor function assessment than the control were signiifcantly higher（P〈0.000）,while the rehabilitation of serum hs-CRP levels were signiifcantly lower than the control group（P〈0.000）. Conclusions：Serum hs-CRP and ACI is closely related to the diagnosis and treatment of CI with high clinical value of early rehabilitation can reduce acute serum hs-CRP levels in patients with CI.

关 键 词：急性脑梗死 早期康复 超敏-CRP 神经功能 

分 类 号：R743.33[医药卫生—神经病学与精神病学]